Cohort studycited by the Tayebat archiveabstract only checked A-SOD-10 standard review

Sugary drinks, weight and diabetes in 91,000 women

Sugar-sweetened beverages, weight gain, and incidence of type 2 diabetes in young and middle-aged women.

Overview

Schulze MB et al.. JAMA 2004 · PMID 15328324 · DOI 10.1001/jama.292.8.927

Women drinking one or more sugary drinks daily had 83% higher diabetes risk; fruit punch similar.

Does the study support the specific claim? Yes · Methodological quality: high

Original publication

Plain-language summary

Study explained simply
What did the researchers want to find out?

Are SSB associated with weight change and T2D in women?

How was the study done?

Prospective cohort (NHS II) 1991-1999.

How many people, animals or samples were studied?

91,249 (diabetes); 51,603 (weight); 741 T2D cases; Women aged young/middle-aged

What was actually found?

Increasing SSB to >=1/day: 4.69 and 4.20 kg weight gain over 4 years vs 1.34 and 0.15 kg in decreasers; >=1 SSB/day T2D RR 1.83 (1.42-2.36); fruit punch RR 2.00 (1.33-3.03).

How large was the observed effect?

RR 1.83 (1.42-2.36)

What do the results mean in everyday life?

Sugary drinks, including fruit punch, are linked with weight gain and diabetes.

What are the study's limitations?

Observational design; residual confounding possible; Self-reported dietary intake

What does it say about Elawady's specific claim?

Supports C-SOD-01, C-SOD-02.

Do the results apply to Germany and Europe?

High.

What can explicitly not be concluded from this study?

Causation.

Scientific in-depth review

1. Full reference

Authors
Schulze MB, Manson JE, Ludwig DS, Colditz GA, Stampfer MJ, Willett WC, Hu FB
Journal
JAMA
Year
2004
Identifier
PMID 15328324 DOI 10.1001/jama.292.8.927
Verification
verified – PubMed E-utilities efetch, 2026-10-25
Retracted
no
Corrections
none
Extent checked
abstract only
Conflicts of interest and funding

No COI statement; NCI grant

2. Research question

Are SSB associated with weight change and T2D in women?

3. Study design and population

Study design
Cohort study – Prospective cohort (NHS II) 1991-1999.
Population

Women aged young/middle-aged

Country

USA

Period

1991-1999

Sample size

91,249 (diabetes); 51,603 (weight); 741 T2D cases

Inclusion and exclusion criteria

Free of diabetes and major chronic disease

4. Methods and endpoints

Exposure / intervention

SSB and fruit punch; change in intake

Comparator

<1/month; stable/decreased intake

Endpoints

Weight gain; incident T2D

Statistical methods

Multivariate models

5. Actual results

Results

Increasing SSB to >=1/day: 4.69 and 4.20 kg weight gain over 4 years vs 1.34 and 0.15 kg in decreasers; >=1 SSB/day T2D RR 1.83 (1.42-2.36); fruit punch RR 2.00 (1.33-3.03).

Absolute risks

741 cases in 716,300 person-years

Authors' conclusion

Higher SSB consumption associated with greater weight gain and increased T2D risk in women.

6. Strengths

  • Large prospective cohort
  • Change analysis

7. Weaknesses

  • Observational design; residual confounding possible
  • Self-reported dietary intake

8. Risk of bias

Orienting tool
ROBINS-E
Type of assessment
simplified assessment (abstract only)
Full formal assessment
no
Overall risk of bias
some concerns
Rationale

Confounding possible.

9. Assessment of the statistical interpretation

Strong relative association.

10. Relevance to the specific claim

Supports C-SOD-01, C-SOD-02.

11. Independent contrary findings

None.

12. Transferability to Germany and Europe

High.

13. Overall methodological judgement

Strong cohort evidence; included in meta-analyses.

Multidimensional assessment
Multidimensional assessment
Authenticity of the sourceverified
Methodological qualityhigh
Risk of biassome concerns
Precision of resultshigh
Directnessdirect
Reproducibilityreplicated
Consistency with the overall evidenceconsistent
Regional transferabilityhigh
Adequacy of the interpretation (by the archive)not applicable

14. Open questions

None specific.

15. Linked fact checks

Use by the Tayebat archive

Note: according to the archive, the studies were compiled by the archive operators. Whether Dr. Elawady himself cited this study is not established.

What the archive says about the study

Listed in the archive bibliography only (no archive interpretation card).

A. What was actually studied?

SSB, weight and T2D.

B. What did the authors find?

As above.

C. What conclusions do the authors themselves draw?

As above.

D. What does the archive derive from it?

Supports weight and diabetes statements.

E. Is this derivation scientifically justified?

Consistent.

Adequacy of the interpretation (by the archive)
not applicable