Case series / case reportcited by the Tayebat archiveabstract only checked★ key study A-VEG-06 in-depth review

Kidney damage from green juicing

Oxalate nephropathy due to 'juicing': case report and review.

Overview

Getting JE et al.. Am J Med 2013 · PMID 23830537 · DOI 10.1016/j.amjmed.2013.03.019

Rare kidney failure from heavy oxalate-rich juicing, mainly in people with kidney disease.

Does the study support the specific claim? Partly · Methodological quality: low

Study explained simply

What did the researchers want to find out?: Describe juicing nephropathy
How was the study done?: Case report + series
How many people, animals or samples were studied?: 65 reviewed patients plus index case report
What was actually found?: Diet cause in 3 with CKD
How large was the observed effect?: Not applicable
What do the results mean in everyday life?: Kidney patients should avoid juice cleanses.
What are the study's limitations?: Case data
What does it say about Elawady's specific claim?: Supports niche risk
Do the results apply to Germany and Europe?: High
What can explicitly not be concluded from this study?: Cannot show risk of normal vegetable intake.

Describe juicing-related oxalate nephropathy and causes of renal oxalosis.

Study design: Case series / case report – Case report and retrospective case series
Population: Index patient + 65 Mayo Clinic patients with biopsy-proven renal CaOx crystals
Country: USA
Period: 1985-2010
Sample size: 65 reviewed Mayo Clinic patients (1985-2010) plus case report; abstract does not state whether the index patient is counted among the 65
Inclusion and exclusion criteria: Biopsy-proven renal oxalosis with renal failure

Results: Cause identified in all 65: single cause in 36, ≥2 causes in 29; 3 patients incl. index had presumed diet-induced oxalate nephropathy in the context of CKD.
Absolute risks: not reported
Authors' conclusion: Oxalate-rich diet may precipitate acute renal failure in CKD; juicing appears to be a potential cause.

Not applicable.

Supports C-VEG-06.

Taylor 2007 for normal intake.

High.

Correct for niche risk.

Multidimensional assessment
Multidimensional assessment
Authenticity of the source	verified
Methodological quality	low
Risk of bias	some concerns
Precision of results	not applicable
Directness	direct
Reproducibility	partly replicated
Consistency with the overall evidence	consistent
Regional transferability	high
Adequacy of the interpretation (by the archive)	essentially correct but incomplete

Frequency.

Note: according to the archive, the studies were compiled by the archive operators. Whether Dr. Elawady himself cited this study is not established.

What the archive says about the study: Heavy juicing (~1,500 mg oxalate/day) caused oxalate nephropathy; oxalate-rich diet can precipitate failure in CKD.
A. What was actually studied?: Case + series.
B. What did the authors find?: Diet-induced cases rare (3/65), in CKD.
C. What conclusions do the authors themselves draw?: Awareness in CKD.
D. What does the archive derive from it?: Greens harm kidneys.
E. Is this derivation scientifically justified?: Correct for extreme juicing in CKD; not for normal intake. 1,500 mg figure not in abstract.
Adequacy of the interpretation (by the archive): essentially correct but incomplete