Risk assessmentindependent cross-checkabstract checked★ key study I-FSH-101 in-depth review

FAO/WHO 2024: benefits and risks of eating fish

Joint FAO/WHO expert consultation on the risks and benefits of fish consumption: meeting report, Rome, 9-13 October 2023 (Food Safety and Quality Series No. 28)

Overview

FAO/WHO. FAO/WHO report 2024 · DOI 10.4060/cd2394en

Strong evidence for benefits of eating fish in pregnancy, childhood and adulthood; methylmercury can reduce the brain benefit in some populations.

Does the study support the specific claim? Partly · Methodological quality: high

Original publication

Plain-language summary

Study explained simply
What did the researchers want to find out?

Update the 2010 benefit-risk conclusions.

How was the study done?

Expert consultation based on a systematic review.

How many people, animals or samples were studied?

Global literature.

What was actually found?

Benefits at all life stages; MeHg can reduce the neurodevelopmental benefit; dioxin evidence mostly from highly exposed groups.

How large was the observed effect?

Not quantified in the parts read.

What do the results mean in everyday life?

Eat fish, and choose species lower in mercury.

What are the study's limitations?

Summary chapters read; no farmed-wild comparison.

What does it say about Elawady's specific claim?

Supports eating fish, but not the idea that any wild sea fish is 'clean'.

Do the results apply to Germany and Europe?

High.

What can explicitly not be concluded from this study?

Species-specific limits for Egypt.

Scientific in-depth review

1. Full reference

Authors
FAO/WHO
Journal
FAO/WHO report
Year
2024
Identifier
DOI 10.4060/cd2394en
Verification
verified – WHO publication page and full PDF (iris.who.int bitstream 029d2553-bc01-4aaa-a4be-422ce33a730a) fetched 2026-10-26; DOI checked via Crossref
Retracted
no
Corrections
none
Extent checked
abstract only
Conflicts of interest and funding

FAO/WHO; experts selected through a global call

2. Research question

What are the health benefits of fish consumption and the risks from methylmercury, dioxins and dl-PCBs, including the role of selenium?

3. Study design and population

Study design
Risk assessment – International expert consultation based on a commissioned systematic literature review (Norwegian Institute of Marine Research); executive summary, conclusions, recommendations and research-gap chapter read
Population

General population; pregnancy, childhood, adulthood

Country

Global

Period

Literature since 2010; meeting October 2023

Sample size

Not applicable

Inclusion and exclusion criteria

Finfish and shellfish, marine or freshwater, farmed or wild; marine mammals and algae excluded

4. Methods and endpoints

Exposure / intervention

Fish consumption; MeHg, dioxins and dl-PCBs in fish

Comparator

Low or no fish consumption

Endpoints

Birth outcomes, neurodevelopment, cardiovascular and neurological disease, toxic effects

Statistical methods

Weight-of-evidence grading

5. Actual results

Results

'Strong evidence exists for the benefits of total fish consumption during all life stages: pregnancy, childhood and adulthood.' 'Maternal fish consumption during pregnancy is associated with improved offspring neurological development, despite evidence from some populations showing that MeHg exposure from fish consumption in early life ... has been associated with less neurodevelopmental benefit expected from fish consumption.' 'Limited evidence of adverse health effects from MeHg exposure' in adulthood. Evidence on dioxins and dl-PCBs is 'mainly from populations highly exposed'. Research gap: future research should differentiate 'capture vs aquaculture'.

Absolute risks

not reported

Authors' conclusion

Member nations should emphasise the benefits of fish across the life course and build regional data on MeHg, dioxins, dl-PCBs and nutrients to refine advice.

6. Strengths

  • Most recent international benefit-risk assessment
  • Based on a systematic review

7. Weaknesses

  • Only summary, conclusion and research-gap chapters read
  • No species-level consumption limits
  • Does not compare farmed and wild fish

8. Risk of bias

Orienting tool
none applicable
Type of assessment
simplified assessment (abstract only)
Full formal assessment
no
Overall risk of bias
not assessable
Rationale

Official expert consultation.

9. Assessment of the statistical interpretation

10. Relevance to the specific claim

C-FSH-14: benefits of fish in pregnancy and childhood; MeHg can reduce the benefit. C-FSH-02: farmed versus wild not differentiated (listed as a data gap).

11. Independent contrary findings

12. Transferability to Germany and Europe

High.

13. Overall methodological judgement

Authoritative; supports eating fish, including in pregnancy, with attention to methylmercury.

Multidimensional assessment
Multidimensional assessment
Authenticity of the sourceverified
Methodological qualityhigh
Risk of biasnot assessable
Precision of resultsnot applicable
Directnessdirect
Reproducibilityreplicated
Consistency with the overall evidenceconsistent
Regional transferabilityhigh
Adequacy of the interpretation (by the archive)not applicable

14. Open questions

15. Linked fact checks