Otherindependent cross-checkabstract checked I-MEAT-110 standard review

Frying boiled meat in saturated fat produced more harmful amines

Frying oils with lower levels of saturated fatty acids induce less heterocyclic amine formation in meat floss (boiled, shredded and fried pork)

Overview

Pan T et al.. Int J Food Sci Technol 2020 · DOI 10.1111/ijfs.14368

Boiled, shredded pork fried in lard or palm oil formed more heterocyclic amines than when fried in soybean oil.

Does the study support the specific claim? No · Methodological quality: moderate

Original publication

Plain-language summary

Study explained simply
What did the researchers want to find out?

Compare frying fats for HCA formation.

How was the study done?

Lab experiment.

How many people, animals or samples were studied?

Meat floss.

What was actually found?

Saturated fats gave more HCAs.

How large was the observed effect?

Significant differences (P < 0.05).

What do the results mean in everyday life?

Boiling first does not stop frying from forming these compounds; the frying fat matters.

What are the study's limitations?

Pork; ghee not tested.

What does it say about Elawady's specific claim?

Questions the 'fry in ghee' step.

Do the results apply to Germany and Europe?

Universal.

What can explicitly not be concluded from this study?

It cannot show health effects.

Scientific in-depth review

1. Full reference

Authors
Pan T et al.
Journal
Int J Food Sci Technol
Year
2020
Identifier
DOI 10.1111/ijfs.14368
Verification
verified – Europe PMC (AGRICOLA record IND606821536) and Crossref works API 2026-10-26; not indexed in PubMed
Retracted
no
Corrections

none (Crossref: no update-to or relation)

Extent checked
abstract only
Conflicts of interest and funding

Not stated in abstract.

2. Research question

Does the type of frying fat affect heterocyclic amine formation in meat that is boiled, shredded and then fried?

3. Study design and population

Study design
Other – Laboratory food chemistry experiment
Population

Pork meat floss

Country

China

Period

not stated in abstract

Sample size

Not applicable

Inclusion and exclusion criteria

not detailed in abstract

4. Methods and endpoints

Exposure / intervention

Frying in lard or palm oil (more saturated)

Comparator

Soybean oil (less saturated)

Endpoints

Heterocyclic amines (Norharman, Harman, AalphaC, MeAalphaC and total)

Statistical methods

Group comparisons (P < 0.05)

5. Actual results

Results

Norharman, Harman, AalphaC and MeAalphaC were higher in meat floss fried with lard and palm oil than with soybean oil; total HCAs with palm oil at 150 C and 180 C were significantly higher than with soybean oil and lard; soybean oil gave the lowest levels at 120-180 C.

Absolute risks

not reported

Authors' conclusion

Soybean oil could replace lard to produce meat floss with fewer HCAs.

6. Strengths

  • Tests the same boil-then-fry sequence

7. Weaknesses

  • Pork product; ghee not tested
  • Laboratory only

8. Risk of bias

Orienting tool
none applicable
Type of assessment
simplified assessment (abstract only)
Full formal assessment
no
Overall risk of bias
not assessable
Rationale

Laboratory study.

9. Assessment of the statistical interpretation

Not applicable.

10. Relevance to the specific claim

Boiled-then-fried meat still forms HCAs during frying, and more saturated frying fats (lard, palm oil) gave more HCAs than soybean oil. Ghee is a highly saturated fat, so frying in ghee is unlikely to be the lowest-HCA choice (ghee itself not tested).

11. Independent contrary findings

For total HCAs, only palm oil (150 and 180 C) was significantly higher than soybean oil and lard; lard raised individual HCAs.

12. Transferability to Germany and Europe

Universal chemistry.

13. Overall methodological judgement

Indirect evidence against the 'fry in ghee' part.

Multidimensional assessment
Multidimensional assessment
Authenticity of the sourceverified
Methodological qualitymoderate
Risk of biasnot assessable
Precision of resultsnot applicable
Directnessindirect
Reproducibilityunknown
Consistency with the overall evidenceunknown
Regional transferabilitymoderate
Adequacy of the interpretation (by the archive)not applicable

14. Open questions

Direct test with ghee and red meat.

15. Linked fact checks