Case-control studycited by the Tayebat archiveabstract only checked A-CHK-07 standard review

Resistant Campylobacter linked to poultry in the US

Fluoroquinolone-resistant Campylobacter infections: eating poultry outside of the home and foreign travel are risk factors.

Overview

Kassenborg HD et al.. Clin Infect Dis 2004 · PMID 15095200 · DOI 10.1086/381597

Domestic resistant infections were linked to eating chicken or turkey at restaurants.

Does the study support the specific claim? Yes · Methodological quality: moderate

Original publication

Plain-language summary

Study explained simply
What did the researchers want to find out?

What are risk factors for fluoroquinolone-resistant Campylobacter infection?

How was the study done?

Population-based case-control study (FoodNet)

How many people, animals or samples were studied?

858 isolates tested; 64 FQ-resistant vs 582 susceptible with travel data; 33 matched case-control pairs; Patients with Campylobacter infection and matched controls

What was actually found?

11% resistant. Travel OR 7.6 (4.3-13.4). Domestic cases: eating chicken or turkey at commercial establishment matched OR 10.0 (1.3-78).

How large was the observed effect?

OR, matched OR

What do the results mean in everyday life?

Poultry can transmit resistant Campylobacter.

What are the study's limitations?

Very wide CI (only 33 pairs); Recall bias

What does it say about Elawady's specific claim?

Supports.

Do the results apply to Germany and Europe?

Moderate.

What can explicitly not be concluded from this study?

Precise risk size.

Scientific in-depth review

1. Full reference

Authors
Kassenborg HD, Smith KE, Vugia DJ, Rabatsky-Ehr T, Bates MR, Carter MA, Dumas NB, Cassidy MP, Marano N, Tauxe RV, Angulo FJ, Emerging Infections Program FoodNet Working Group
Journal
Clin Infect Dis
Year
2004
Identifier
PMID 15095200 DOI 10.1086/381597
Verification
verified – PubMed E-utilities efetch, 2026-10-25
Retracted
no
Corrections
none
Extent checked
abstract only
Conflicts of interest and funding

No COI statement in record

2. Research question

What are risk factors for fluoroquinolone-resistant Campylobacter infection?

3. Study design and population

Study design
Case-control study – Population-based case-control study (FoodNet)
Population

Patients with Campylobacter infection and matched controls

Country

USA

Period

1998-1999

Sample size

858 isolates tested; 64 FQ-resistant vs 582 susceptible with travel data; 33 matched case-control pairs

Inclusion and exclusion criteria

FoodNet areas

4. Methods and endpoints

Exposure / intervention

Travel; eating poultry outside home

Comparator

Susceptible infections; healthy controls

Endpoints

FQ-resistant Campylobacter infection

Statistical methods

OR, matched OR

5. Actual results

Results

11% resistant. Travel OR 7.6 (4.3-13.4). Domestic cases: eating chicken or turkey at commercial establishment matched OR 10.0 (1.3-78).

Absolute risks

not applicable

Authors' conclusion

Poultry is an important source of domestically acquired FQ-resistant Campylobacter.

6. Strengths

  • Population-based

7. Weaknesses

  • Very wide CI (only 33 pairs)
  • Recall bias

8. Risk of bias

Orienting tool
ROBINS-E
Type of assessment
simplified assessment (abstract only)
Full formal assessment
no
Overall risk of bias
some concerns
Rationale

Small numbers; recall bias.

9. Assessment of the statistical interpretation

OR 10 with CI 1.3-78 is imprecise.

10. Relevance to the specific claim

C-CHK-05, C-CHK-09.

11. Independent contrary findings

None.

12. Transferability to Germany and Europe

Moderate.

13. Overall methodological judgement

Supports claim.

Multidimensional assessment
Multidimensional assessment
Authenticity of the sourceverified
Methodological qualitymoderate
Risk of biassome concerns
Precision of resultslow
Directnessdirect
Reproducibilitypartly replicated
Consistency with the overall evidenceconsistent
Regional transferabilitymoderate
Adequacy of the interpretation (by the archive)not applicable

14. Open questions

None.

15. Linked fact checks

Use by the Tayebat archive

Note: according to the archive, the studies were compiled by the archive operators. Whether Dr. Elawady himself cited this study is not established.

What the archive says about the study

Listed in bibliography (no interpretation).

A. What was actually studied?

Risk factors for FQ-resistant Campylobacter.

B. What did the authors find?

Travel and restaurant poultry associated.

C. What conclusions do the authors themselves draw?

Poultry important source.

D. What does the archive derive from it?

Supports resistant bacteria from poultry.

E. Is this derivation scientifically justified?

Justified.

Adequacy of the interpretation (by the archive)
not applicable