Case-control studycited by the Tayebat archiveabstract only checked A-CHK-07 standard review
Resistant Campylobacter linked to poultry in the US
Fluoroquinolone-resistant Campylobacter infections: eating poultry outside of the home and foreign travel are risk factors.
Overview
Kassenborg HD et al.. Clin Infect Dis 2004 · PMID 15095200 · DOI 10.1086/381597
Domestic resistant infections were linked to eating chicken or turkey at restaurants.
Does the study support the specific claim? Yes · Methodological quality: moderate
Plain-language summary
Study explained simply
- What did the researchers want to find out?
What are risk factors for fluoroquinolone-resistant Campylobacter infection?
- How was the study done?
Population-based case-control study (FoodNet)
- How many people, animals or samples were studied?
858 isolates tested; 64 FQ-resistant vs 582 susceptible with travel data; 33 matched case-control pairs; Patients with Campylobacter infection and matched controls
- What was actually found?
11% resistant. Travel OR 7.6 (4.3-13.4). Domestic cases: eating chicken or turkey at commercial establishment matched OR 10.0 (1.3-78).
- How large was the observed effect?
OR, matched OR
- What do the results mean in everyday life?
Poultry can transmit resistant Campylobacter.
- What are the study's limitations?
Very wide CI (only 33 pairs); Recall bias
- What does it say about Elawady's specific claim?
Supports.
- Do the results apply to Germany and Europe?
Moderate.
- What can explicitly not be concluded from this study?
Precise risk size.
Scientific in-depth review
1. Full reference
- Authors
- Kassenborg HD, Smith KE, Vugia DJ, Rabatsky-Ehr T, Bates MR, Carter MA, Dumas NB, Cassidy MP, Marano N, Tauxe RV, Angulo FJ, Emerging Infections Program FoodNet Working Group
- Journal
- Clin Infect Dis
- Year
- 2004
- Identifier
- PMID 15095200 DOI 10.1086/381597
- Verification
- verified – PubMed E-utilities efetch, 2026-10-25
- Retracted
- no
- Corrections
- none
- Extent checked
- abstract only
- Conflicts of interest and funding
No COI statement in record
2. Research question
What are risk factors for fluoroquinolone-resistant Campylobacter infection?
3. Study design and population
- Study design
- Case-control study – Population-based case-control study (FoodNet)
- Population
Patients with Campylobacter infection and matched controls
- Country
USA
- Period
1998-1999
- Sample size
858 isolates tested; 64 FQ-resistant vs 582 susceptible with travel data; 33 matched case-control pairs
- Inclusion and exclusion criteria
FoodNet areas
4. Methods and endpoints
- Exposure / intervention
Travel; eating poultry outside home
- Comparator
Susceptible infections; healthy controls
- Endpoints
FQ-resistant Campylobacter infection
- Statistical methods
OR, matched OR
5. Actual results
- Results
11% resistant. Travel OR 7.6 (4.3-13.4). Domestic cases: eating chicken or turkey at commercial establishment matched OR 10.0 (1.3-78).
- Absolute risks
not applicable
- Authors' conclusion
Poultry is an important source of domestically acquired FQ-resistant Campylobacter.
6. Strengths
- Population-based
7. Weaknesses
- Very wide CI (only 33 pairs)
- Recall bias
8. Risk of bias
- Orienting tool
- ROBINS-E
- Type of assessment
- simplified assessment (abstract only)
- Full formal assessment
- no
- Overall risk of bias
- some concerns
- Rationale
Small numbers; recall bias.
9. Assessment of the statistical interpretation
OR 10 with CI 1.3-78 is imprecise.
10. Relevance to the specific claim
11. Independent contrary findings
None.
12. Transferability to Germany and Europe
Moderate.
13. Overall methodological judgement
Supports claim.
| Multidimensional assessment | |
|---|---|
| Authenticity of the source | verified |
| Methodological quality | moderate |
| Risk of bias | some concerns |
| Precision of results | low |
| Directness | direct |
| Reproducibility | partly replicated |
| Consistency with the overall evidence | consistent |
| Regional transferability | moderate |
| Adequacy of the interpretation (by the archive) | not applicable |
14. Open questions
None.
15. Linked fact checks
- Industrial chicken is raised with routine antibiotics, and antibiotic-resistant bacteria (e.g., ESBL E. coli, MRSA, resistant Campylobacter, mcr-1) spread from poultry to humans via the food chain. – Studies supporting the claim
- Chicken carries Campylobacter and Salmonella, which cause human infections. – Studies supporting the claim
Use by the Tayebat archive
Note: according to the archive, the studies were compiled by the archive operators. Whether Dr. Elawady himself cited this study is not established.
- What the archive says about the study
Listed in bibliography (no interpretation).
- A. What was actually studied?
Risk factors for FQ-resistant Campylobacter.
- B. What did the authors find?
Travel and restaurant poultry associated.
- C. What conclusions do the authors themselves draw?
Poultry important source.
- D. What does the archive derive from it?
Supports resistant bacteria from poultry.
- E. Is this derivation scientifically justified?
Justified.
- Adequacy of the interpretation (by the archive)
- not applicable