Narrative reviewcited by the Tayebat archiveabstract only checked A-FSH-12 standard review

Fish farming as a route for resistance

Aquaculture as yet another environmental gateway to the development and globalisation of antimicrobial resistance.

Overview

Cabello FC et al.. Lancet Infect Dis 2016 · PMID 27083976 · DOI 10.1016/S1473-3099(16)00100-6

Aquaculture antibiotics can help resistance spread globally.

Does the study support the specific claim? Yes · Methodological quality: moderate

Original publication

Plain-language summary

Study explained simply
What did the researchers want to find out?

Review.

How was the study done?

Narrative.

What was actually found?

Resistance spread.

What do the results mean in everyday life?

Stewardship needed.

What are the study's limitations?

Not quantitative.

What does it say about Elawady's specific claim?

Supports concern.

Do the results apply to Germany and Europe?

Moderate.

What can explicitly not be concluded from this study?

Human burden size.

Scientific in-depth review

1. Full reference

Authors
Cabello FC, Godfrey HP, Buschmann AH, Dölz HJ
Journal
Lancet Infect Dis
Year
2016
Identifier
PMID 27083976 DOI 10.1016/S1473-3099(16)00100-6
Verification
verified – PubMed E-utilities efetch, 2026-10-25
Retracted
no
Corrections
none
Extent checked
abstract only
Conflicts of interest and funding

not stated in abstract/record

2. Research question

Role of aquaculture in AMR globalisation

3. Study design and population

Study design
Narrative review – Review: aquaculture as gateway for AMR
Country

Global

Period

2016

4. Methods and endpoints

Exposure / intervention

Aquaculture antimicrobials

5. Actual results

Results

Hundreds of tonnes used annually; selection and horizontal transfer of resistance; calls for vaccines, probiotics, phage.

Absolute risks

not reported

Authors' conclusion

Prevent overuse through One Health measures.

6. Strengths

  • Lancet ID

7. Weaknesses

  • Narrative

8. Risk of bias

Orienting tool
none applicable
Type of assessment
simplified assessment (abstract only)
Full formal assessment
no
Overall risk of bias
some concerns

9. Assessment of the statistical interpretation

10. Relevance to the specific claim

C-FSH-08.

11. Independent contrary findings

12. Transferability to Germany and Europe

Moderate.

13. Overall methodological judgement

Supports concern.

Multidimensional assessment
Multidimensional assessment
Authenticity of the sourceverified
Methodological qualitymoderate
Risk of biassome concerns
Precision of resultsnot applicable
Directnessindirect
Reproducibilitypartly replicated
Consistency with the overall evidenceconsistent
Regional transferabilitymoderate
Adequacy of the interpretation (by the archive)essentially correct but incomplete

14. Open questions

15. Linked fact checks

Use by the Tayebat archive

Note: according to the archive, the studies were compiled by the archive operators. Whether Dr. Elawady himself cited this study is not established.

What the archive says about the study

Bibliography only.

A. What was actually studied?

AMR gateway.

B. What did the authors find?

Selection and transfer.

C. What conclusions do the authors themselves draw?

Prevent overuse.

D. What does the archive derive from it?

Supports antibiotic concern.

E. Is this derivation scientifically justified?

Justified.

Adequacy of the interpretation (by the archive)
essentially correct but incomplete