Ecological studycited by the Tayebat archiveabstract only checked★ key study A-ORG-19 in-depth review

US thyroid cancer: more diagnoses, same deaths

Current thyroid cancer trends in the United States.

Overview

Davies L et al.. JAMA Otolaryngol Head Neck Surg 2014 · PMID 24557566 · DOI 10.1001/jamaoto.2014.1

Diagnoses nearly tripled from 1975 to 2009 while deaths stayed at about 0.5 per 100,000.

Does the study support the specific claim? Yes · Methodological quality: high

Original publication

Plain-language summary

Study explained simply
What did the researchers want to find out?

Overdiagnosis

How was the study done?

Trend analysis

How many people, animals or samples were studied?

SEER 9

What was actually found?

Incidence up, mortality flat

How large was the observed effect?

RR 2.9

What do the results mean in everyday life?

Many small cancers found would never have caused harm

What are the study's limitations?

Ecological

What does it say about Elawady's specific claim?

Supports

Do the results apply to Germany and Europe?

Similar in Europe (not verified here)

What can explicitly not be concluded from this study?

Which individual tumours are harmless

Scientific in-depth review

1. Full reference

Authors
Davies L, Welch HG
Journal
JAMA Otolaryngol Head Neck Surg
Year
2014
Identifier
PMID 24557566 DOI 10.1001/jamaoto.2014.1
Verification
verified – PubMed E-utilities efetch, 2026-10-25
Retracted
no
Corrections
none
Extent checked
abstract only
Conflicts of interest and funding

COI: not stated in record | Grants: none listed

2. Research question

Has thyroid cancer incidence stabilized?

3. Study design and population

Study design
Ecological study – Ecological secular-trend analysis (SEER 9) with national mortality data
Population

Adults in 9 SEER areas

Country

USA

Period

1975-2009

4. Methods and endpoints

5. Actual results

Results

Incidence 4.9 -> 14.3 per 100,000 (RR 2.9; 2.7-3.1); papillary 3.4 -> 12.5 (RR 3.7); women increase 14.9 vs men 3.8 per 100,000; mortality stable ~0.5 per 100,000.

Absolute risks

Absolute increase 9.4 per 100,000

Authors' conclusion

Ongoing epidemic of diagnosis rather than disease; particularly acute for women.

6. Strengths

  • Population registry
  • Consistent with autopsy and screening data

7. Weaknesses

  • Ecological; cannot prove individual overdiagnosis

8. Risk of bias

Orienting tool
none applicable
Type of assessment
simplified assessment (abstract only)
Full formal assessment
no
Overall risk of bias
low

9. Assessment of the statistical interpretation

10. Relevance to the specific claim

Supports C-ORG-14.

11. Independent contrary findings

12. Transferability to Germany and Europe

Similar trends reported internationally (Vaccarella 2016; not abstracted).

13. Overall methodological judgement

Correctly cited.

Multidimensional assessment
Multidimensional assessment
Authenticity of the sourceverified
Methodological qualityhigh
Risk of biaslow
Precision of resultshigh
Directnessdirect
Reproducibilityreplicated
Consistency with the overall evidenceconsistent
Regional transferabilitymoderate
Adequacy of the interpretation (by the archive)essentially correct but incomplete

14. Open questions

15. Linked fact checks

Use by the Tayebat archive

Note: according to the archive, the studies were compiled by the archive operators. Whether Dr. Elawady himself cited this study is not established.

What the archive says about the study

US thyroid cancer incidence tripled while mortality stayed flat — an epidemic of diagnosis driving avoidable thyroidectomies.

A. What was actually studied?

Thyroid cancer trends

B. What did the authors find?

Incidence nearly tripled; mortality flat

C. What conclusions do the authors themselves draw?

Epidemic of diagnosis

D. What does the archive derive from it?

Used to argue that screening-driven thyroid surgery is often unnecessary.

E. Is this derivation scientifically justified?

Numbers correct. 'Avoidable thyroidectomies' is a reasonable inference (overdiagnosis leads to overtreatment) but is not measured in this study.

Adequacy of the interpretation (by the archive)
essentially correct but incomplete