Meta-analysisindependent cross-checkabstract only checked I-DRY-09 standard review
78,529 young people: dairy of all kinds linked to acne
Dairy Intake and Acne Vulgaris: A Systematic Review and Meta-Analysis of 78,529 Children, Adolescents, and Young Adults.
Overview
Juhl CR et al.. Nutrients 2018 · PMID 30096883 · DOI 10.3390/nu10081049
Any dairy OR 1.25; cheese 1.22; yogurt 1.36.
Does the study support the specific claim? Partly · Methodological quality: moderate
Plain-language summary
Study explained simply
- What did the researchers want to find out?
Dairy and acne.
- How was the study done?
Meta-analysis.
- How many people, animals or samples were studied?
78,529 young people.
- What was actually found?
All dairy types associated.
- How large was the observed effect?
OR 1.25 (1.15-1.36).
- What do the results mean in everyday life?
Possible link; cheese included.
- What are the study's limitations?
Publication bias.
- What does it say about Elawady's specific claim?
Supports association; no milk-vs-cheese split.
- Do the results apply to Germany and Europe?
Moderate.
- What can explicitly not be concluded from this study?
Causation.
Scientific in-depth review
1. Full reference
- Authors
- Juhl CR et al.
- Journal
- Nutrients
- Year
- 2018
- Identifier
- PMID 30096883 DOI 10.3390/nu10081049
- Verification
- verified – PubMed efetch 2026-10-25
- Retracted
- no
- Corrections
- none
- Extent checked
- abstract only
- Conflicts of interest and funding
G.B.E.J. has received honoraria from AbbVie, MSD, Pfizer, Pierre-Fabre, and UCB for participation on advisory boards, and grants from Abbvie, Actelion, Janssen-Cilag, Leo Pharma, Novartis, and Regeneron for participation as an investigator, and received speaker honoraria from AbbVie, Galderma, Leo Pharma, and MSD. He has furthermore received unrestricted research grants from AbbVie and Leo Pharma. He has received travel grants from AbbVie, Celgene, Desitin, and Novartis. GBEJ’s sponsors were not involved in any parts of this article (design, conduct, collection, management, analysis, interpretation, preparation, approval, review, decision to submit). H.K.M.B. has received a grant from the Danish Dairy Research Foundation. None of the funding agencies had any role in the design, analysis, or writing of this article.
2. Research question
Dairy intake and acne in ages 7-30.
3. Study design and population
- Study design
- Meta-analysis – Systematic review and meta-analysis of observational studies.
- Population
Children, adolescents, young adults
- Country
Multinational
- Period
Search to 11 Dec 2017
- Sample size
14 studies; 78,529 (23,046 cases)
- Inclusion and exclusion criteria
Observational studies, ages 7-30.
4. Methods and endpoints
- Exposure / intervention
Dairy, milk types, cheese, yogurt
- Comparator
No intake/less than weekly
- Endpoints
Acne.
- Statistical methods
Random effects; publication bias tests.
5. Actual results
- Results
Any dairy OR 1.25 (1.15-1.36); any milk 1.28 (1.13-1.44); low-fat/skim 1.32 (1.16-1.52); cheese 1.22 (1.00-1.50); yogurt 1.36 (1.05-1.77); >=2 glasses/day 1.43 (1.09-1.88). Publication bias (p=0.0047); adjusted results attenuated.
- Absolute risks
not reported
- Authors' conclusion
Any dairy associated with increased OR for acne; interpret with caution due to heterogeneity and bias.
6. Strengths
- Large sample
- Bias assessment
7. Weaknesses
- Publication bias
- Unadjusted estimates
8. Risk of bias
- Orienting tool
- AMSTAR 2
- Type of assessment
- simplified assessment (abstract only)
- Full formal assessment
- no
- Overall risk of bias
- some concerns
- Rationale
Publication bias found.
9. Assessment of the statistical interpretation
Modest ORs, attenuated after adjustment.
10. Relevance to the specific claim
Supporting C-DRY-08; shows cheese also associated.
11. Independent contrary findings
I-DRY-08 (no yogurt/cheese association).
12. Transferability to Germany and Europe
Includes European data (Danish authors).
13. Overall methodological judgement
Consistent but biased observational evidence.
| Multidimensional assessment | |
|---|---|
| Authenticity of the source | verified |
| Methodological quality | moderate |
| Risk of bias | some concerns |
| Precision of results | high |
| Directness | direct |
| Reproducibility | partly replicated |
| Consistency with the overall evidence | consistent |
| Regional transferability | moderate |
| Adequacy of the interpretation (by the archive) | not applicable |
14. Open questions
RCTs.
15. Linked fact checks
- Milk intake (especially skim milk) causes acne in teenagers. – Studies supporting the claim