Randomised controlled trialindependent cross-checkabstract checked I-EGG-106 standard review
An egg a day did not change growth in Malawian babies
The effect of eggs on early child growth in rural Malawi: the Mazira Project randomized controlled trial.
Overview
Stewart CP et al.. Am J Clin Nutr 2019 · PMID 31386106 · DOI 10.1093/ajcn/nqz163
No overall effect on length or weight after 6 months.
Does the study support the specific claim? Unclear · Methodological quality: high
Plain-language summary
Study explained simply
- What did the researchers want to find out?
Test eggs for growth.
- How was the study done?
Randomized trial.
- How many people, animals or samples were studied?
660 infants.
- What was actually found?
No effect on growth overall.
- How large was the observed effect?
Head circumference z +0.18.
- What do the results mean in everyday life?
Eggs are not a magic growth food, but nothing suggests they harmed the children.
- What are the study's limitations?
Low stunting at baseline.
- What does it say about Elawady's specific claim?
Neither supports nor clearly refutes harm; balances the Ecuador result.
- Do the results apply to Germany and Europe?
Limited.
- What can explicitly not be concluded from this study?
It cannot show that eggs are harmful.
Scientific in-depth review
1. Full reference
- Authors
- Stewart CP et al.
- Journal
- Am J Clin Nutr
- Year
- 2019
- Identifier
- PMID 31386106 DOI 10.1093/ajcn/nqz163
- Verification
- verified – PubMed efetch 2026-10-26; Crossref works API 2026-10-26
- Retracted
- no
- Corrections
- none
- Extent checked
- abstract only
- Conflicts of interest and funding
NIDDK/NIH and non-US government support (PubMed).
2. Research question
Does one egg per day improve growth of children aged 6-9 months in rural Malawi?
3. Study design and population
- Study design
- Randomised controlled trial – Individually randomized controlled trial with blinded outcome assessment, 6 months
- Population
Children aged 6-9 months, rural Malawi
- Country
Malawi
- Period
Randomization February-July 2018
- Sample size
660 (331 egg, 329 control); 10% loss to follow-up
- Inclusion and exclusion criteria
not detailed in abstract
4. Methods and endpoints
- Exposure / intervention
1 egg per day for 6 months
- Comparator
Control with equal visit frequency
- Endpoints
Length-for-age, weight-for-age, weight-for-length, head circumference z scores
- Statistical methods
Intention-to-treat comparisons
5. Actual results
- Results
No intervention effect on length-for-age, weight-for-age or weight-for-length z scores; head circumference-for-age z +0.18 (0.01-0.34); effect on length only among children of mothers with higher education (interaction P = 0.024). Egg consumption rose to 84.5% (3 months) and 70.3% (6 months) in the intervention group.
- Absolute risks
not reported
- Authors' conclusion
Providing 1 egg per day had no overall effect on linear growth; a background diet rich in animal source foods and low stunting may have limited the impact.
6. Strengths
- Larger trial; blinded assessors
- Registered (NCT03385252)
7. Weaknesses
- Low baseline stunting
- Adherence declined
8. Risk of bias
- Orienting tool
- RoB 2
- Type of assessment
- simplified assessment (abstract only)
- Full formal assessment
- no
- Overall risk of bias
- low
- Rationale
Blinded outcome assessment; simplified judgement.
9. Assessment of the statistical interpretation
Null primary results with adequate power; head circumference effect small and secondary.
10. Relevance to the specific claim
Provides balance: eggs did not improve growth in this setting, so benefits should not be overstated. The abstract does not report harms.
11. Independent contrary findings
Ecuador trial positive (I-EGG-105).
12. Transferability to Germany and Europe
Low-income setting.
13. Overall methodological judgement
Shows that the growth benefit of eggs is context-dependent; does not indicate harm.
| Multidimensional assessment | |
|---|---|
| Authenticity of the source | verified |
| Methodological quality | high |
| Risk of bias | low |
| Precision of results | moderate |
| Directness | indirect |
| Reproducibility | not replicated |
| Consistency with the overall evidence | inconsistent |
| Regional transferability | moderate |
| Adequacy of the interpretation (by the archive) | not applicable |
14. Open questions
Adverse events not reported in abstract.
15. Linked fact checks
- All eggs (chicken, quail, pigeon, ostrich, etc.) are harmful because an egg is an embryo / contains the 'full components of a living organism'. – Studies with mixed or unclear results