Cohort studyindependent cross-checkabstract checked I-GRN-119 standard review

French fries were linked to high blood pressure, chips were not

Potato intake and incidence of hypertension: results from three prospective US cohort studies.

Overview

Borgi L et al.. BMJ 2016 · PMID 27189229 · DOI 10.1136/bmj.i2351

In 187,000 US adults, eating French fries 4+ times a week was linked to 17% higher hypertension risk.

Does the study support the specific claim? Partly · Methodological quality: moderate

Original publication

Plain-language summary

Study explained simply
What did the researchers want to find out?

Potatoes and hypertension.

How was the study done?

Three cohorts.

How many people, animals or samples were studied?

187,453 adults.

What was actually found?

Fries linked; chips not.

How large was the observed effect?

HR 1.17 for fries.

What do the results mean in everyday life?

Limit fried potatoes.

What are the study's limitations?

Self-report.

What does it say about Elawady's specific claim?

Contradicts unrestricted fried potatoes.

Do the results apply to Germany and Europe?

Moderate.

What can explicitly not be concluded from this study?

Cannot prove causation.

Scientific in-depth review

1. Full reference

Authors
Borgi L et al.
Journal
BMJ
Year
2016
Identifier
PMID 27189229 DOI 10.1136/bmj.i2351 · PMC4870381
Verification
verified – PubMed efetch 2026-10-26; Crossref works API 2026-10-26
Retracted
no
Corrections
none
Extent checked
abstract only
Conflicts of interest and funding

No financial relationships declared

2. Research question

Are baked/boiled potatoes, French fries or potato chips associated with incident hypertension?

3. Study design and population

Study design
Cohort study – Three prospective cohorts (NHS, NHS II, HPFS)
Population

Non-hypertensive US adults

Country

USA

Period

not stated in abstract

Sample size

187,453 (62,175 + 88,475 + 36,803)

Inclusion and exclusion criteria

Non-hypertensive at baseline

4. Methods and endpoints

Exposure / intervention

Potato intake by type

Comparator

<1 serving/month

Endpoints

Incident hypertension (self-report)

Statistical methods

Cox models; random-effects pooling; substitution analysis

5. Actual results

Results

>=4 servings/week vs <1/month: baked/boiled/mashed HR 1.11 (0.96-1.28; P trend 0.05); French fries 1.17 (1.07-1.27; P trend 0.001); potato chips 0.97 (0.87-1.08). Replacing one daily serving of baked/boiled/mashed potatoes with non-starchy vegetables: HR 0.93 (0.89-0.96).

Absolute risks

not reported

Authors' conclusion

Higher intake of baked, boiled or mashed potatoes and French fries was independently associated with hypertension.

6. Strengths

  • Large cohorts, long follow-up

7. Weaknesses

  • Self-reported hypertension
  • Observational

8. Risk of bias

Orienting tool
ROBINS-E
Type of assessment
simplified assessment (abstract only)
Full formal assessment
no
Overall risk of bias
some concerns
Rationale

Residual confounding.

9. Assessment of the statistical interpretation

Small relative risks; chips null for hypertension.

10. Relevance to the specific claim

Fried potatoes associated with hypertension; chips not.

11. Independent contrary findings

I-GRN-120 (total potato not associated with hypertension).

12. Transferability to Germany and Europe

Moderate.

13. Overall methodological judgement

Moderate-quality observational evidence.

Multidimensional assessment
Multidimensional assessment
Authenticity of the sourceverified
Methodological qualitymoderate
Risk of biassome concerns
Precision of resultshigh
Directnessdirect
Reproducibilitypartly replicated
Consistency with the overall evidencemixed
Regional transferabilitymoderate
Adequacy of the interpretation (by the archive)not applicable

14. Open questions

Causality.

15. Linked fact checks