Ecological studyindependent cross-checkfull text checked★ key study I-SRC-105 in-depth review

Measles in the Eastern Mediterranean 2023-2024

Measles and Rubella Elimination Trends in the WHO Eastern Mediterranean Region, 2023-2024: Progress and Recent Epidemiological Shifts.

Overview

Farid M et al.. Vaccines (Basel) 2026 · PMID 42646678 · DOI 10.3390/vaccines14080659

Egypt, with about 96% of children vaccinated twice, had no measles in 2024, while low-coverage neighbours had large outbreaks.

Does the study support the specific claim? No · Methodological quality: moderate

Original publication

Plain-language summary

Study explained simply
What did the researchers want to find out?

Track measles elimination in the region

How was the study done?

Analysis of WHO surveillance data

How many people, animals or samples were studied?

22 countries

What was actually found?

Outbreaks where coverage is low; elimination in Egypt

How large was the observed effect?

Egypt 0 cases per million in 2024

What do the results mean in everyday life?

High vaccination keeps measles away

What are the study's limitations?

Descriptive data; under-reporting

What does it say about Elawady's specific claim?

Contradicts banning vaccines

Do the results apply to Germany and Europe?

Egypt-specific

What can explicitly not be concluded from this study?

Causal effect size (not a trial)

Scientific in-depth review

1. Full reference

Authors
Farid M et al.
Journal
Vaccines (Basel)
Year
2026
Identifier
PMID 42646678 DOI 10.3390/vaccines14080659
Verification
verified – PubMed efetch 2026-10-26; Crossref works record checked
Retracted
no
Corrections
none
Extent checked
full text
Conflicts of interest and funding

Authors declare no conflict of interest; WHO-affiliated authors' views are their own.

2. Research question

What progress has the WHO Eastern Mediterranean Region made toward measles and rubella elimination in 2023-2024?

3. Study design and population

Study design
Ecological study – Retrospective descriptive analysis of WHO surveillance and coverage data (22 countries)
Population

22 EMR countries including Egypt

Country

WHO Eastern Mediterranean Region (incl. Egypt)

Period

2023-2024

Sample size

22 countries; 111,760 measles cases with age and vaccination status

Inclusion and exclusion criteria

All EMR countries

4. Methods and endpoints

Exposure / intervention

MCV1/MCV2 coverage

Comparator

Between countries and years

Endpoints

Measles/rubella incidence, coverage, elimination status

Statistical methods

Descriptive

5. Actual results

Results

Regional measles incidence rose from 110.8 to 116.3 per million; large outbreaks in Yemen, Iraq and Afghanistan. 72.9% of cases in children under 5, many zero-dose or one-dose; cases with >=2 doses comparatively low. Egypt: MCV1/MCV2 coverage 96%/95% (2023) and 97%/96% (2024); measles incidence 2.2 per million (2023) and 0 (2024); Egypt verified as having sustained measles and rubella elimination for 2024.

Absolute risks

Egypt measles incidence 0 per million in 2024 (Table 1).

Authors' conclusion

The EMR remains off track for elimination; equity-focused strengthening of routine immunisation is needed.

6. Strengths

  • Official WHO data for all countries
  • Egypt-specific figures
  • Full text read

7. Weaknesses

  • Descriptive, ecological
  • Under-reporting acknowledged
  • Coverage data discrepancies

8. Risk of bias

Orienting tool
none applicable
Type of assessment
simplified assessment (abstract only)
Full formal assessment
no
Overall risk of bias
some concerns
Rationale

Surveillance data quality varies by country (authors' limitation).

9. Assessment of the statistical interpretation

No inferential statistics; the contrast between high-coverage Egypt (elimination) and low-coverage conflict settings (large outbreaks) is descriptive but consistent with vaccine trial evidence (I-INTB-16).

10. Relevance to the specific claim

Egypt-specific: with about 95-97% two-dose coverage, measles was eliminated in Egypt, while neighbouring low-coverage countries had large outbreaks mainly among unvaccinated children. A vaccination ban would remove this protection.

11. Independent contrary findings

None.

12. Transferability to Germany and Europe

Regional (Egypt/EMR).

13. Overall methodological judgement

Strong regional context supporting vaccination.

Multidimensional assessment
Multidimensional assessment
Authenticity of the sourceverified
Methodological qualitymoderate
Risk of biassome concerns
Precision of resultsnot applicable
Directnessdirect
Reproducibilityunknown
Consistency with the overall evidenceconsistent
Regional transferabilityhigh
Adequacy of the interpretation (by the archive)not applicable

14. Open questions

15. Linked fact checks