Mostly true Certainty of evidence: low provisional C-ORG-09

Bilateral oophorectomy at hysterectomy for benign disease increases all-cause mortality, coronary disease and lung cancer — roughly one extra death per nine operations (Parker 2013, Nurses' Health Study).

Conclusion: Direction supported; the 'one in nine' figure is misquoted and over-generalized.

Original statement

باركر في Nurses' Health Study على 30,117 ممرضة وثّق ارتفاع الوفيات الكلية ومرض الشريان التاجي وسرطان الرئة بعد استئصال المبيضين الثنائي لمرض حميد.

verbatim according to source. Translation by the project; the Arabic wording is authoritative.

Translation

Bilateral oophorectomy at hysterectomy for benign disease increases all-cause mortality, coronary disease and lung cancer — roughly one extra death per nine operations (Parker 2013, Nurses' Health Study).

Origin

Source status
Archive editors
Attribution
Archive editors (eltayebat.com); not necessarily Elawady's own words
Origin
https://eltayebat.com/rule/unnecessary-organ-removal/
Attribution uncertainty
Editorial summary/narrative and study selection written by the archive operators; the archive states that the cited research documents harm independently of Dr. Diaa's words.
Claimed mechanism

Loss of ovarian hormones.

Claimed health effect

Higher mortality, CHD, lung cancer.

Population concerned

Women undergoing benign hysterectomy

Geographic restriction by Elawady

not applicable

Scientific assessment

Mostly true – Correct at its core, but with limitations or minor inaccuracies.

Certainty of evidence: low – Further research is likely to change the assessment considerably.

1. What was claimed?

Oophorectomy raises mortality, CHD and lung cancer; NNH about 9.

2. What is demonstrably correct?

All-cause death 16.8% vs 13.3% (HR 1.13); in women <50 never using estrogen HR 1.41 with NNH 8 (A-ORG-13); multimorbidity HR 1.22 (A-ORG-15); meta-analysis: total CVD HR 1.18, CHD 1.17 (I-ORG-10).

3. What is wrong or exaggerated?

The NNH '9' is not reported; the paper's NNH (8) is restricted to a subgroup and does not apply to all women. Oophorectomy also reduced ovarian cancer deaths (4 vs 44). In the meta-analysis (I-ORG-10), excess all-cause mortality was seen only for BSO before age 50 (HR 1.22, I2 85%) and not after 50 (HR 0.98, 0.91-1.05); lung cancer was not among the pooled outcomes, and no 'one extra death per nine operations' figure is supported; the same review reports strong reductions in ovarian cancer (HR 0.11) and breast cancer before 45 (HR 0.78).

4. What remains unclear?

Causality (reasons for oophorectomy unknown).

5. Which studies support it?

A-ORG-13, A-ORG-15, I-ORG-10.

6. Which studies contradict it?

I-ORG-10 (mortality heterogeneity; breast cancer benefit).

7. What applies to Germany and Europe?

Most cited cohorts are Scandinavian (Denmark, Sweden) and directly European; RCTs from the UK and Finland are directly transferable. Guidelines in Europe also emphasize defined indications (not verified here in detail).

8. What is known about Egypt?

No Egypt-specific data on rates or outcomes of tonsillectomy, cholecystectomy, hysterectomy, splenectomy or thyroid surgery were identified in this review.

9. What practical conclusion is appropriate?

Removing healthy ovaries at benign hysterectomy in younger women has long-term costs; decisions should be individual.

Assessment details

Rationale for certainty of evidence

Consistent observational evidence and a meta-analysis for CVD; mortality evidence heterogeneous; NNH misquoted.

Source quality

Direction correct. 'One extra death per nine operations' is not in the paper; NNH 8 applies only to women <50 who never used estrogen.

Regional transferability

US data; European registers similar for CVD.

Individual exceptions

No excess mortality among estrogen users in Parker; oophorectomy lowers ovarian and (before 47.5) breast cancer death; women with high genetic risk (e.g., BRCA) are a different situation.

Regional scope of the claim
general (biological/medical)
Last reviewed
25 October 2026 provisional

In plain language

The archive says that removing both ovaries during a hysterectomy for a benign condition increases deaths and heart disease, with one extra death per nine operations. The direction is supported by large studies, especially for women under 50 who do not take estrogen. But the 'one in nine' figure is not in the study: the study gives one extra death per 8 operations only for that subgroup. Removing ovaries also lowered deaths from ovarian cancer.

Studies on this claim

Studies supporting the claim (2)

  • Nurses' Health Study: removing both ovaries at hysterectomy

    Parker WH et al.. Obstet Gynecol 2013 · PMID 23635669 · DOI 10.1097/AOG.0b013e3182864350
    Cohort studycited by the Tayebat archivefull text checked★ key study

    Removing the ovaries was linked to somewhat higher death rates (16.8% vs 13.3% over 28 years), mainly in women under 50 who never took estrogen.

    Does the study support the specific claim? Partly · Methodological quality: moderate · Certainty of evidence: see overall assessment of the claim

    Original publication · Scientific details

    Study explained simply
    What did the researchers want to find out?

    Mortality

    How was the study done?

    Prospective cohort

    How many people, animals or samples were studied?

    30,117

    What was actually found?

    Higher mortality, especially <50 without estrogen

    How large was the observed effect?

    HR 1.13; NNH 8 in subgroup

    What do the results mean in everyday life?

    Keeping healthy ovaries may be better for many women

    What are the study's limitations?

    Observational

    What does it say about Elawady's specific claim?

    Supports direction; NNH misused

    Do the results apply to Germany and Europe?

    Applicable

    What can explicitly not be concluded from this study?

    Causation; women with BRCA etc.

    Scientific details →

  • Ovary removal and chronic diseases

    Rocca WA et al.. Mayo Clin Proc 2016 · PMID 27693001 · DOI 10.1016/j.mayocp.2016.08.002
    Cohort studycited by the Tayebat archiveabstract only checked

    Women who had both ovaries removed before 46 accumulated chronic diseases faster.

    Does the study support the specific claim? Yes · Methodological quality: moderate · Certainty of evidence: see overall assessment of the claim

    Original publication · Scientific details

    Study explained simply
    What did the researchers want to find out?

    Multimorbidity

    How was the study done?

    Cohort

    How many people, animals or samples were studied?

    n/a

    What was actually found?

    Faster accumulation

    How large was the observed effect?

    HR 1.22

    What do the results mean in everyday life?

    Possible broad health cost

    What are the study's limitations?

    Baseline differences

    What does it say about Elawady's specific claim?

    Supports

    Do the results apply to Germany and Europe?

    Applicable

    What can explicitly not be concluded from this study?

    Causation

    Scientific details →

Studies contradicting or limiting the claim (0)

No studies in this group.

Studies with mixed or unclear results (1)

  • Meta-analysis: removing ovaries at hysterectomy

    Hassan H et al.. Am J Obstet Gynecol 2024 · PMID 37364803 · DOI 10.1016/j.ajog.2023.06.043
    Meta-analysisindependent cross-checkfull text checked★ key study

    Linked to less breast cancer but more heart disease, dementia and other conditions in younger women; effect on death was inconsistent.

    Does the study support the specific claim? Partly · Methodological quality: moderate · Certainty of evidence: see overall assessment of the claim

    Original publication · Scientific details

    Study explained simply
    What did the researchers want to find out?

    BSO outcomes

    How was the study done?

    Meta-analysis

    How many people, animals or samples were studied?

    n/a

    What was actually found?

    Trade-offs

    How large was the observed effect?

    CVD HR 1.18; dementia HR 1.70

    What do the results mean in everyday life?

    Removing healthy ovaries in young women has costs and some benefits

    What are the study's limitations?

    Observational studies, few per outcome, fixed-effect pooling, no study-level risk-of-bias assessment

    What does it say about Elawady's specific claim?

    Supports risks; mortality unclear

    Do the results apply to Germany and Europe?

    Applicable

    What can explicitly not be concluded from this study?

    Causation; harm after age 50; absolute risk

    Scientific details →

Regional context

Germany / EU

Most cited cohorts are Scandinavian (Denmark, Sweden) and directly European; RCTs from the UK and Finland are directly transferable. Guidelines in Europe also emphasize defined indications (not verified here in detail).

Egypt

No Egypt-specific data on rates or outcomes of tonsillectomy, cholecystectomy, hysterectomy, splenectomy or thyroid surgery were identified in this review.

What applies in my country?

General scientific assessment

Mostly true Direction supported; the 'one in nine' figure is misquoted and over-generalized.

This statement concerns biological or medical relationships. The scientific assessment above applies regardless of the country; country-specific food data do not change it.

References

  1. Long-term mortality associated with oophorectomy compared with ovarian conservation in the nurses' health study.. Parker WH et al.. Obstet Gynecol 2013 · PMID 23635669 · DOI 10.1097/AOG.0b013e3182864350
  2. Accelerated Accumulation of Multimorbidity After Bilateral Oophorectomy: A Population-Based Cohort Study.. Rocca WA et al.. Mayo Clin Proc 2016 · PMID 27693001 · DOI 10.1016/j.mayocp.2016.08.002
  3. Long-term outcomes of hysterectomy with bilateral salpingo-oophorectomy: a systematic review and meta-analysis.. Hassan H et al.. Am J Obstet Gynecol 2024 · PMID 37364803 · DOI 10.1016/j.ajog.2023.06.043

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