Cohort studycited by the Tayebat archiveabstract only checked A-BAR-06 standard review

7 years after bypass or band

Seven-Year Weight Trajectories and Health Outcomes in the Longitudinal Assessment of Bariatric Surgery (LABS) Study.

Overview

Courcoulas AP et al.. JAMA Surg 2018 · PMID 29214306 · DOI 10.1001/jamasurg.2017.5025

About 60% of bypass patients with diabetes were still in remission at 7 years.

Does the study support the specific claim? Partly · Methodological quality: moderate

Original publication

Plain-language summary

Study explained simply
What did the researchers want to find out?

Durability

How was the study done?

Cohort

How many people, animals or samples were studied?

2348

What was actually found?

Remission 71%->60% (RYGB)

How large was the observed effect?

see results

What do the results mean in everyday life?

Most keep benefit, some relapse

What are the study's limitations?

No control

What does it say about Elawady's specific claim?

Partly supports erosion claim

Do the results apply to Germany and Europe?

Applicable

What can explicitly not be concluded from this study?

Comparison with non-surgical care

Scientific in-depth review

1. Full reference

Authors
Courcoulas AP, King WC, Belle SH, Berk P, Flum DR, Garcia L, Gourash W, Horlick M, Mitchell JE, Pomp A, Pories WJ, Purnell JQ, Singh A, Spaniolas K, Thirlby R, Wolfe BM, Yanovski SZ
Journal
JAMA Surg
Year
2018
Identifier
PMID 29214306 DOI 10.1001/jamasurg.2017.5025 · PMC6584318
Verification
verified – PubMed E-utilities efetch, 2026-10-25
Retracted
no
Corrections
none
Extent checked
abstract only
Conflicts of interest and funding

COI: not stated in record | Grants: NCRR NIH HHS, NIDDK NIH HHS

2. Research question

Long-term weight and health after RYGB and LAGB

3. Study design and population

Study design
Cohort study – Multicentre observational cohort (LABS-2), up to 7 years
Population

US adults undergoing bariatric surgery

Country

USA

Period

2006-2015

Sample size

2348 (1738 RYGB, 610 LAGB)

Inclusion and exclusion criteria

Clinical-care bariatric patients at 10 hospitals

4. Methods and endpoints

Exposure / intervention

RYGB, LAGB

Comparator

Baseline (pre-post)

Endpoints

Weight change, diabetes, dyslipidemia, hypertension

Statistical methods

Trajectory modelling; proportions with 95% CI

5. Actual results

Results

RYGB weight loss at 7 years 28.4% (27.6-29.2), regain 3.9% between years 3-7. Diabetes remission after RYGB 71.2% (1 y), 69.4% (3 y), 64.6% (5 y), 60.2% (7 y); LAGB 30.7% -> 20.3%. Diabetes incidence after RYGB <1.5%. Reoperations 14 RYGB, 160 LAGB.

Absolute risks

Remission 60.2% at 7 y after RYGB

Authors' conclusion

Most maintained weight loss; some decline in diabetes remission, low incidence of new diabetes after RYGB.

6. Strengths

  • Large, multicentre
  • Good follow-up (83% at year 7)

7. Weaknesses

  • No non-surgical control
  • No sleeve gastrectomy

8. Risk of bias

Orienting tool
ROBINS-E
Type of assessment
simplified assessment (abstract only)
Full formal assessment
no
Overall risk of bias
some concerns
Rationale

Pre-post design without control.

9. Assessment of the statistical interpretation

Gradual decline of remission (71% -> 60%).

10. Relevance to the specific claim

Shows modest decline in remission over 7 years.

11. Independent contrary findings

12. Transferability to Germany and Europe

Applicable with caution.

13. Overall methodological judgement

Supports that remission declines but mostly persists to 7 years.

Multidimensional assessment
Multidimensional assessment
Authenticity of the sourceverified
Methodological qualitymoderate
Risk of biassome concerns
Precision of resultshigh
Directnessdirect
Reproducibilityreplicated
Consistency with the overall evidenceconsistent
Regional transferabilitymoderate
Adequacy of the interpretation (by the archive)not applicable

14. Open questions

15. Linked fact checks

Use by the Tayebat archive

Note: according to the archive, the studies were compiled by the archive operators. Whether Dr. Elawady himself cited this study is not established.

What the archive says about the study

Listed in the archive bibliography only; the archive gives no specific interpretation.

A. What was actually studied?

7-year outcomes

B. What did the authors find?

Remission declined modestly (71%->60%)

C. What conclusions do the authors themselves draw?

Some decline but durable

D. What does the archive derive from it?

Not used explicitly.

E. Is this derivation scientifically justified?

Not applicable; the data show slower erosion than the archive's 'within a few years' wording suggests.

Adequacy of the interpretation (by the archive)
not applicable