Cohort studycited by the Tayebat archiveabstract only checked A-BAR-06 standard review
7 years after bypass or band
Seven-Year Weight Trajectories and Health Outcomes in the Longitudinal Assessment of Bariatric Surgery (LABS) Study.
Overview
Courcoulas AP et al.. JAMA Surg 2018 · PMID 29214306 · DOI 10.1001/jamasurg.2017.5025
About 60% of bypass patients with diabetes were still in remission at 7 years.
Does the study support the specific claim? Partly · Methodological quality: moderate
Plain-language summary
Study explained simply
- What did the researchers want to find out?
Durability
- How was the study done?
Cohort
- How many people, animals or samples were studied?
2348
- What was actually found?
Remission 71%->60% (RYGB)
- How large was the observed effect?
see results
- What do the results mean in everyday life?
Most keep benefit, some relapse
- What are the study's limitations?
No control
- What does it say about Elawady's specific claim?
Partly supports erosion claim
- Do the results apply to Germany and Europe?
Applicable
- What can explicitly not be concluded from this study?
Comparison with non-surgical care
Scientific in-depth review
1. Full reference
- Authors
- Courcoulas AP, King WC, Belle SH, Berk P, Flum DR, Garcia L, Gourash W, Horlick M, Mitchell JE, Pomp A, Pories WJ, Purnell JQ, Singh A, Spaniolas K, Thirlby R, Wolfe BM, Yanovski SZ
- Journal
- JAMA Surg
- Year
- 2018
- Identifier
- PMID 29214306 DOI 10.1001/jamasurg.2017.5025 · PMC6584318
- Verification
- verified – PubMed E-utilities efetch, 2026-10-25
- Retracted
- no
- Corrections
- none
- Extent checked
- abstract only
- Conflicts of interest and funding
COI: not stated in record | Grants: NCRR NIH HHS, NIDDK NIH HHS
2. Research question
Long-term weight and health after RYGB and LAGB
3. Study design and population
- Study design
- Cohort study – Multicentre observational cohort (LABS-2), up to 7 years
- Population
US adults undergoing bariatric surgery
- Country
USA
- Period
2006-2015
- Sample size
2348 (1738 RYGB, 610 LAGB)
- Inclusion and exclusion criteria
Clinical-care bariatric patients at 10 hospitals
4. Methods and endpoints
- Exposure / intervention
RYGB, LAGB
- Comparator
Baseline (pre-post)
- Endpoints
Weight change, diabetes, dyslipidemia, hypertension
- Statistical methods
Trajectory modelling; proportions with 95% CI
5. Actual results
- Results
RYGB weight loss at 7 years 28.4% (27.6-29.2), regain 3.9% between years 3-7. Diabetes remission after RYGB 71.2% (1 y), 69.4% (3 y), 64.6% (5 y), 60.2% (7 y); LAGB 30.7% -> 20.3%. Diabetes incidence after RYGB <1.5%. Reoperations 14 RYGB, 160 LAGB.
- Absolute risks
Remission 60.2% at 7 y after RYGB
- Authors' conclusion
Most maintained weight loss; some decline in diabetes remission, low incidence of new diabetes after RYGB.
6. Strengths
- Large, multicentre
- Good follow-up (83% at year 7)
7. Weaknesses
- No non-surgical control
- No sleeve gastrectomy
8. Risk of bias
- Orienting tool
- ROBINS-E
- Type of assessment
- simplified assessment (abstract only)
- Full formal assessment
- no
- Overall risk of bias
- some concerns
- Rationale
Pre-post design without control.
9. Assessment of the statistical interpretation
Gradual decline of remission (71% -> 60%).
10. Relevance to the specific claim
Shows modest decline in remission over 7 years.
11. Independent contrary findings
12. Transferability to Germany and Europe
Applicable with caution.
13. Overall methodological judgement
Supports that remission declines but mostly persists to 7 years.
| Multidimensional assessment | |
|---|---|
| Authenticity of the source | verified |
| Methodological quality | moderate |
| Risk of bias | some concerns |
| Precision of results | high |
| Directness | direct |
| Reproducibility | replicated |
| Consistency with the overall evidence | consistent |
| Regional transferability | moderate |
| Adequacy of the interpretation (by the archive) | not applicable |
14. Open questions
15. Linked fact checks
Use by the Tayebat archive
Note: according to the archive, the studies were compiled by the archive operators. Whether Dr. Elawady himself cited this study is not established.
- What the archive says about the study
Listed in the archive bibliography only; the archive gives no specific interpretation.
- A. What was actually studied?
7-year outcomes
- B. What did the authors find?
Remission declined modestly (71%->60%)
- C. What conclusions do the authors themselves draw?
Some decline but durable
- D. What does the archive derive from it?
Not used explicitly.
- E. Is this derivation scientifically justified?
Not applicable; the data show slower erosion than the archive's 'within a few years' wording suggests.
- Adequacy of the interpretation (by the archive)
- not applicable