Meta-analysiscited by the Tayebat archiveabstract only checked A-WHT-18 standard review

White rice and diabetes, heart disease, cancer

White rice consumption and risk of cardiometabolic and cancer outcomes: A systematic review and dose-response meta-analysis of prospective cohort studies.

Overview

Lai H et al.. Crit Rev Food Sci Nutr 2023 · PMID 35852223 · DOI 10.1080/10408398.2022.2101984

More white rice linked to more diabetes (16 more cases per 1000), not to heart disease or cancer.

Does the study support the specific claim? No · Methodological quality: moderate

Original publication

Plain-language summary

Study explained simply
What did the researchers want to find out?

White rice outcomes

How was the study done?

Meta-analysis

How many people, animals or samples were studied?

1.5 million

What was actually found?

T2D up; others null

How large was the observed effect?

RR 1.18

What do the results mean in everyday life?

Moderate rice fine; large intakes raise diabetes risk modestly

What are the study's limitations?

Observational

What does it say about Elawady's specific claim?

Conflicts with unlimited rice

Do the results apply to Germany and Europe?

Moderate

What can explicitly not be concluded from this study?

Cause

Scientific in-depth review

1. Full reference

Authors
Lai H, Sun M, Liu Y, Zhu H, Li M, Pan B, Wang Q, Yang Q, Cao X, Tian C, Lu Y, Song X, Ding G, Tian J, Yang K, Ge L
Journal
Crit Rev Food Sci Nutr
Year
2023
Identifier
PMID 35852223 DOI 10.1080/10408398.2022.2101984
Verification
verified – PubMed E-utilities efetch, 2026-10-25
Retracted
no
Corrections
none
Extent checked
abstract only
Conflicts of interest and funding

None stated.

2. Research question

White rice and cardiometabolic/cancer outcomes

3. Study design and population

Study design
Meta-analysis – Systematic review, dose-response meta-analysis with GRADE
Population

Cohorts

Country

Multiple

Period

not stated

Sample size

23 articles, 28 cohorts, 1,527,198 participants

4. Methods and endpoints

Exposure / intervention

White rice

Comparator

Lowest

Endpoints

T2D, CVD, cancer, MetS

Statistical methods

Random effects; GRADE

5. Actual results

Results

T2D highest vs lowest RR 1.18 (16 more per 1000 persons; moderate certainty); females 23 more per 1000; +150 g/day: 6% higher risk (5 more per 1000). No significant associations with CVD, CVD mortality, cancer, MetS (low to very low certainty).

Absolute risks

16 more T2D cases per 1000 persons (highest vs lowest); 5 more per 1000 per 150 g/day

Authors' conclusion

Moderate certainty that white rice is associated with T2D; no substantial associations for other outcomes.

6. Strengths

  • GRADE
  • absolute effects

7. Weaknesses

  • Observational

8. Risk of bias

Orienting tool
AMSTAR 2
Type of assessment
simplified assessment (abstract only)
Full formal assessment
no
Overall risk of bias
some concerns

9. Assessment of the statistical interpretation

Absolute effect small.

10. Relevance to the specific claim

Contradicts C-GRN-05.

11. Independent contrary findings

12. Transferability to Germany and Europe

Moderate.

13. Overall methodological judgement

Modest T2D association.

Multidimensional assessment
Multidimensional assessment
Authenticity of the sourceverified
Methodological qualitymoderate
Risk of biassome concerns
Precision of resultsmoderate
Directnessdirect
Reproducibilityreplicated
Consistency with the overall evidenceconsistent
Regional transferabilitymoderate
Adequacy of the interpretation (by the archive)taken out of context

14. Open questions

15. Linked fact checks

Use by the Tayebat archive

Note: according to the archive, the studies were compiled by the archive operators. Whether Dr. Elawady himself cited this study is not established.

What the archive says about the study

Listed in bibliography only.

D. What does the archive derive from it?

Cited under white-flour rule.

E. Is this derivation scientifically justified?

Contradicts the system's unrestricted rice allowance; archive does not reconcile.

Adequacy of the interpretation (by the archive)
taken out of context