Guideline / position statementindependent cross-checkfull text checked I-CHK-06 standard review

IARC on red and processed meat

Carcinogenicity of consumption of red and processed meat.

Overview

Bouvard V et al.. Lancet Oncol 2015 · PMID 26514947 · DOI 10.1016/S1470-2045(15)00444-1

Processed meat causes cancer and red meat probably does; poultry was not evaluated; cooking method evidence was insufficient.

Does the study support the specific claim? Unclear · Methodological quality: high

Original publication

Plain-language summary

Study explained simply
What did the researchers want to find out?

Carcinogenicity of red and processed meat

How was the study done?

IARC Monographs Working Group evaluation (summary) and IARC Q&A

How many people, animals or samples were studied?

Not applicable; Human evidence base

What was actually found?

Processed meat Group 1 (colorectal cancer; ~18% higher risk per 50 g/day); red meat Group 2A. Q&A: "The cancer risks associated with consumption of poultry and fish were not evaluated." High-temperature cooking produces more PAHs and HAAs, but there were not enough data to conclude whether cooking method affects cancer risk.

How large was the observed effect?

Not applicable

What do the results mean in everyday life?

Chicken is not on the IARC carcinogen list.

What are the study's limitations?

Poultry not evaluated

What does it say about Elawady's specific claim?

Limits the claim.

Do the results apply to Germany and Europe?

High.

What can explicitly not be concluded from this study?

Cannot clear poultry either.

Scientific in-depth review

1. Full reference

Authors
Bouvard V et al.
Journal
Lancet Oncol
Year
2015
Identifier
PMID 26514947 DOI 10.1016/S1470-2045(15)00444-1
Verification
verified – PubMed efetch 2026-10-25 (no abstract); content read from IARC Monographs Q&A Vol. 114 PDF fetched 2026-10-25: https://www.iarc.who.int/wp-content/uploads/2018/07/Monographs-QA_Vol114.pdf
Retracted
no
Corrections
none
Extent checked
full text
Conflicts of interest and funding

WHO/NCI funding

2. Research question

Carcinogenicity of red and processed meat

3. Study design and population

Study design
Guideline / position statement – IARC Monographs Working Group evaluation (summary) and IARC Q&A
Population

Human evidence base

Country

International

Period

October 2015

Sample size

Not applicable

Inclusion and exclusion criteria

IARC criteria

4. Methods and endpoints

Exposure / intervention

Red meat, processed meat

Comparator

Not applicable

Endpoints

Carcinogenicity classification

Statistical methods

Not applicable

5. Actual results

Results

Processed meat Group 1 (colorectal cancer; ~18% higher risk per 50 g/day); red meat Group 2A. Q&A: "The cancer risks associated with consumption of poultry and fish were not evaluated." High-temperature cooking produces more PAHs and HAAs, but there were not enough data to conclude whether cooking method affects cancer risk.

Absolute risks

Per 50 g/day processed meat ~18% higher colorectal cancer risk (relative)

Authors' conclusion

See results.

6. Strengths

  • Authoritative

7. Weaknesses

  • Poultry not evaluated

8. Risk of bias

Orienting tool
none applicable
Type of assessment
simplified assessment (abstract only)
Full formal assessment
no
Overall risk of bias
not assessable
Rationale

Hazard classification.

9. Assessment of the statistical interpretation

Hazard identification, not risk magnitude.

10. Relevance to the specific claim

C-CHK-01, C-CHK-10.

11. Independent contrary findings

Not applicable.

12. Transferability to Germany and Europe

High.

13. Overall methodological judgement

Poultry not classified; cooking-method evidence insufficient.

Multidimensional assessment
Multidimensional assessment
Authenticity of the sourceverified
Methodological qualityhigh
Risk of biaslow
Precision of resultsnot applicable
Directnessindirect
Reproducibilityreplicated
Consistency with the overall evidenceconsistent
Regional transferabilityhigh
Adequacy of the interpretation (by the archive)not applicable

14. Open questions

Poultry and HCAs.

15. Linked fact checks