Guideline / position statementindependent cross-checkfull text checked I-CHK-06 standard review
IARC on red and processed meat
Carcinogenicity of consumption of red and processed meat.
Overview
Bouvard V et al.. Lancet Oncol 2015 · PMID 26514947 · DOI 10.1016/S1470-2045(15)00444-1
Processed meat causes cancer and red meat probably does; poultry was not evaluated; cooking method evidence was insufficient.
Does the study support the specific claim? Unclear · Methodological quality: high
Plain-language summary
Study explained simply
- What did the researchers want to find out?
Carcinogenicity of red and processed meat
- How was the study done?
IARC Monographs Working Group evaluation (summary) and IARC Q&A
- How many people, animals or samples were studied?
Not applicable; Human evidence base
- What was actually found?
Processed meat Group 1 (colorectal cancer; ~18% higher risk per 50 g/day); red meat Group 2A. Q&A: "The cancer risks associated with consumption of poultry and fish were not evaluated." High-temperature cooking produces more PAHs and HAAs, but there were not enough data to conclude whether cooking method affects cancer risk.
- How large was the observed effect?
Not applicable
- What do the results mean in everyday life?
Chicken is not on the IARC carcinogen list.
- What are the study's limitations?
Poultry not evaluated
- What does it say about Elawady's specific claim?
Limits the claim.
- Do the results apply to Germany and Europe?
High.
- What can explicitly not be concluded from this study?
Cannot clear poultry either.
Scientific in-depth review
1. Full reference
- Authors
- Bouvard V et al.
- Journal
- Lancet Oncol
- Year
- 2015
- Identifier
- PMID 26514947 DOI 10.1016/S1470-2045(15)00444-1
- Verification
- verified – PubMed efetch 2026-10-25 (no abstract); content read from IARC Monographs Q&A Vol. 114 PDF fetched 2026-10-25: https://www.iarc.who.int/wp-content/uploads/2018/07/Monographs-QA_Vol114.pdf
- Retracted
- no
- Corrections
- none
- Extent checked
- full text
- Conflicts of interest and funding
WHO/NCI funding
2. Research question
Carcinogenicity of red and processed meat
3. Study design and population
- Study design
- Guideline / position statement – IARC Monographs Working Group evaluation (summary) and IARC Q&A
- Population
Human evidence base
- Country
International
- Period
October 2015
- Sample size
Not applicable
- Inclusion and exclusion criteria
IARC criteria
4. Methods and endpoints
- Exposure / intervention
Red meat, processed meat
- Comparator
Not applicable
- Endpoints
Carcinogenicity classification
- Statistical methods
Not applicable
5. Actual results
- Results
Processed meat Group 1 (colorectal cancer; ~18% higher risk per 50 g/day); red meat Group 2A. Q&A: "The cancer risks associated with consumption of poultry and fish were not evaluated." High-temperature cooking produces more PAHs and HAAs, but there were not enough data to conclude whether cooking method affects cancer risk.
- Absolute risks
Per 50 g/day processed meat ~18% higher colorectal cancer risk (relative)
- Authors' conclusion
See results.
6. Strengths
- Authoritative
7. Weaknesses
- Poultry not evaluated
8. Risk of bias
- Orienting tool
- none applicable
- Type of assessment
- simplified assessment (abstract only)
- Full formal assessment
- no
- Overall risk of bias
- not assessable
- Rationale
Hazard classification.
9. Assessment of the statistical interpretation
Hazard identification, not risk magnitude.
10. Relevance to the specific claim
11. Independent contrary findings
Not applicable.
12. Transferability to Germany and Europe
High.
13. Overall methodological judgement
Poultry not classified; cooking-method evidence insufficient.
| Multidimensional assessment | |
|---|---|
| Authenticity of the source | verified |
| Methodological quality | high |
| Risk of bias | low |
| Precision of results | not applicable |
| Directness | indirect |
| Reproducibility | replicated |
| Consistency with the overall evidence | consistent |
| Regional transferability | high |
| Adequacy of the interpretation (by the archive) | not applicable |
14. Open questions
Poultry and HCAs.
15. Linked fact checks
- Chicken is forbidden because it is harmful in itself, not because of how it is raised (it is 'the pig of birds'); its fibres and waste products are hard to digest. – Studies contradicting or limiting the claim
- Grilling or pan-frying chicken breast forms potent carcinogens (PhIP up to 480 ng/g). – Studies with mixed or unclear results