Systematic reviewindependent cross-checkabstract only checked I-INTA-12 in-depth review

What causes bad breath?

Aetiology and associations of halitosis: A systematic review.

Overview

Memon MA et al.. Oral diseases 2023 · PMID 35212093 · DOI 10.1111/odi.14172

80-90% of bad breath comes from the mouth itself (tongue coating, gum disease, poor hygiene).

Does the study support the specific claim? No · Methodological quality: moderate

Original publication

Plain-language summary

Study explained simply
What did the researchers want to find out?

Causes of halitosis

How was the study done?

Systematic review

How many people, animals or samples were studied?

Studies 2014-2020

What was actually found?

Mostly intra-oral causes

How large was the observed effect?

80-90% intra-oral

What do the results mean in everyday life?

Bad breath is usually treated in the mouth, not by avoiding eggs

What are the study's limitations?

Narrative synthesis

What does it say about Elawady's specific claim?

Contradicts eggs as a general cause of bad breath

Do the results apply to Germany and Europe?

High

What can explicitly not be concluded from this study?

Individual food-related odours

Scientific in-depth review

1. Full reference

Authors
Memon MA et al.
Journal
Oral diseases
Year
2023
Identifier
PMID 35212093 DOI 10.1111/odi.14172
Verification
verified – PubMed efetch 2026-10-25
Retracted
no
Corrections
none
Extent checked
abstract only
Conflicts of interest and funding

not stated in abstract

2. Research question

Intra-oral and extra-oral causes and associations of halitosis

3. Study design and population

Study design
Systematic review – Systematic review
Population

Studies on people with halitosis

Country

Multinational

Period

January 2014 to December 2020

Sample size

not stated in abstract

Inclusion and exclusion criteria

MEDLINE, Google Scholar, Wiley; studies on causes of oral malodour

4. Methods and endpoints

Exposure / intervention

Intra-oral and extra-oral factors

Comparator

Not applicable

Endpoints

Halitosis

Statistical methods

Narrative synthesis

5. Actual results

Results

80-90% of halitosis is caused by intra-oral factors (coated tongue, periodontal disease, poor oral hygiene); 10-20% by extra-oral factors associated with systemic diseases.

Absolute risks

Not applicable

Authors' conclusion

Most halitosis is of intra-oral origin.

6. Strengths

  • Systematic search

7. Weaknesses

  • Narrative synthesis
  • Limited time window

8. Risk of bias

Orienting tool
AMSTAR 2
Type of assessment
simplified assessment (abstract only)
Full formal assessment
no
Overall risk of bias
some concerns
Rationale

Simplified.

9. Assessment of the statistical interpretation

Proportions summarised from included studies.

10. Relevance to the specific claim

Bad breath mainly has oral causes; eggs are not an established cause.

11. Independent contrary findings

Food odours can cause transient breath odour (not assessed here).

12. Transferability to Germany and Europe

High.

13. Overall methodological judgement

Reliable overview.

Multidimensional assessment
Multidimensional assessment
Authenticity of the sourceverified
Methodological qualitymoderate
Risk of biassome concerns
Precision of resultsnot applicable
Directnessindirect
Reproducibilityreplicated
Consistency with the overall evidenceconsistent
Regional transferabilityhigh
Adequacy of the interpretation (by the archive)not applicable

14. Open questions

None for this claim.

15. Linked fact checks