Systematic reviewindependent cross-checkabstract only checked I-SYS-08 standard review

Slow breathing calms body and mind in short studies

How Breath-Control Can Change Your Life: A Systematic Review on Psycho-Physiological Correlates of Slow Breathing.

Overview

Zaccaro A et al.. Front Hum Neurosci 2018 · PMID 30245619 · DOI 10.3389/fnhum.2018.00353

Small studies show more relaxation and heart-rate variability.

Does the study support the specific claim? Partly · Methodological quality: low

Original publication

Plain-language summary

Study explained simply
What did the researchers want to find out?

Review slow-breathing effects.

How was the study done?

Systematic review.

How many people, animals or samples were studied?

15 studies.

What was actually found?

Relaxation effects.

What do the results mean in everyday life?

Breathing exercises are a harmless relaxation aid.

What are the study's limitations?

Small studies.

What does it say about Elawady's specific claim?

Partial support.

Do the results apply to Germany and Europe?

High.

What can explicitly not be concluded from this study?

Disease prevention or cure.

Scientific in-depth review

1. Full reference

Authors
Zaccaro A et al.
Journal
Front Hum Neurosci
Year
2018
Identifier
PMID 30245619 DOI 10.3389/fnhum.2018.00353
Verification
verified – PubMed esummary + efetch 2026-10-25
Retracted
no
Corrections
none
Extent checked
abstract only
Conflicts of interest and funding

not stated

2. Research question

Psychophysiological effects of slow breathing.

3. Study design and population

Study design
Systematic review – Systematic review (15 studies, healthy subjects)
Population

Healthy subjects

Country

International

Sample size

15 studies

Inclusion and exclusion criteria

Slow breathing <10/min; healthy

4. Methods and endpoints

Exposure / intervention

Slow breathing

Comparator

Various

Endpoints

HRV, EEG, psychological outcomes

Statistical methods

Narrative synthesis

5. Actual results

Results

Slow breathing increased heart-rate variability and respiratory sinus arrhythmia; EEG alpha increased; more relaxation, comfort, vigour; less anxiety, depression, anger.

Absolute risks

not applicable

Authors' conclusion

Slow breathing enhances autonomic and psychological flexibility.

6. Strengths

  • PRISMA

7. Weaknesses

  • Few small studies
  • Healthy subjects; no hard outcomes

8. Risk of bias

Orienting tool
AMSTAR 2
Type of assessment
simplified assessment (abstract only)
Full formal assessment
no
Overall risk of bias
high
Rationale

Small heterogeneous primary studies.

9. Assessment of the statistical interpretation

Short-term physiological/psychological effects only.

10. Relevance to the specific claim

Low-certainty support for breathing exercises as relaxation.

11. Independent contrary findings

12. Transferability to Germany and Europe

High.

13. Overall methodological judgement

Plausible, low-risk practice; no disease-treatment evidence.

Multidimensional assessment
Multidimensional assessment
Authenticity of the sourceverified
Methodological qualitylow
Risk of biashigh
Precision of resultslow
Directnessindirect
Reproducibilitypartly replicated
Consistency with the overall evidencemixed
Regional transferabilityhigh
Adequacy of the interpretation (by the archive)not applicable

14. Open questions

15. Linked fact checks