Ayam industri dipelihara dengan antibiotik secara rutin, dan bakteri yang resistan terhadap antibiotik (mis. E. coli ESBL, MRSA, Campylobacter resistan, mcr-1) menyebar dari unggas ke manusia melalui rantai makanan.
Pernyataan asli
فهو مُربّى بالمضادات الحيوية وأدوية الزرنيخ ... ويحمل بكتيريا متعددة المقاومة تنتقل إلى الإنسان عبر السلسلة الغذائية
kata demi kata sesuai sumber. Terjemahan oleh proyek; rumusan bahasa Arab yang menjadi acuan.
Terjemahan
Ayam industri dipelihara dengan antibiotik secara rutin, dan bakteri yang resistan terhadap antibiotik (mis. E. coli ESBL, MRSA, Campylobacter resistan, mcr-1) menyebar dari unggas ke manusia melalui rantai makanan.
Asal
- Status sumber
- Redaksi arsip
- Atribusi
- Archive editors (not Elawady)
- Asal
- https://eltayebat.com/rule/industrial-chicken/
- Ketidakpastian atribusi
- Narrative and study selection written by the archive operators; the archive states the forbidden section is documented independently of Dr. Diaa's words.
- Mekanisme yang diklaim
Routine/sub-therapeutic antibiotic use selects resistant bacteria that reach humans via meat.
- Efek kesehatan yang diklaim
Infections with resistant bacteria; loss of last-resort antibiotics.
- Populasi yang dimaksud
general population (not specified)
- Batasan geografis oleh Elawady
none found
Versi sumber yang berbeda
- Status sumber
- Transkrip video (kata-katanya sendiri)
- Atribusi
- Elawady (machine transcript)
- Video
- Dr Diaa Al Awady د ضياء العوضي is live! الالتهاب ايه هوه ؟ (Buka sumber)
- Dipublikasikan
- 26 September 2025
- Penanda waktu
- tidak tersedia (transkrip tidak memiliki penanda waktu)
- Ketidakpastian atribusi
- Archive transcript (YouTube CC or AI-generated); wording may contain transcription errors; no timestamps available.
- Status sumber
- Transkrip video (kata-katanya sendiri)
- Atribusi
- Elawady (machine transcript)
- Video
- البكتيريا النافعة ؟! Bacterial Flora , What do we know about it ? (Buka sumber)
- Dipublikasikan
- 11 Januari 2025
- Penanda waktu
- tidak tersedia (transkrip tidak memiliki penanda waktu)
- Ketidakpastian atribusi
- Archive transcript (YouTube CC or AI-generated); wording may contain transcription errors; no timestamps available.
- Status sumber
- Transkrip video (kata-katanya sendiri)
- Atribusi
- Elawady (machine transcript)
- Video
- ودي الحلقه التانيه من البودكاست…حلقه استثنائيه وقولولي رأيكوا (Buka sumber)
- Dipublikasikan
- 10 April 2026
- Penanda waktu
- tidak tersedia (transkrip tidak memiliki penanda waktu)
- Ketidakpastian atribusi
- Archive transcript (YouTube CC or AI-generated); wording may contain transcription errors; no timestamps available.
Penilaian ilmiah
Sebagian besar benar – Benar pada intinya, tetapi dengan keterbatasan atau ketidaktepatan kecil.
Tingkat kepastian bukti: sedang – Penelitian lebih lanjut masih dapat memengaruhi penilaian.
1. Apa yang diklaim?
Chickens are raised on routine antibiotics and pass multidrug-resistant bacteria to humans.
2. Apa yang terbukti benar?
Global livestock antibiotic use was estimated at 63,151 tons (2010), projected +67% by 2030 (A-CHK-05). Dutch data: 94% of retail chicken samples contained ESBL producers, with poultry-type genes in human isolates (A-CHK-02, A-CHK-03). mcr-1 was found in Chinese animals, meat and patients (A-CHK-11). Restricting antibiotic use lowers resistance in animals and was associated with lower prevalence in humans (I-CHK-01). The 2023-2024 EU report found rising ciprofloxacin resistance in poultry-associated Salmonella and C. jejuni from humans in more than half of reporting countries (I-CHK-116). WHO recommends ending antibiotic use for growth promotion and prevention (I-CHK-118). In Egypt, all 111 surveyed farms used antimicrobials, 65% for non-therapeutic purposes, and half used colistin (I-CHK-117).
3. Apa yang salah atau dilebih-lebihkan?
'Routine antibiotics' is not a uniform reality: the EU banned antibiotics as growth promoters from 2006 and restricts preventive use. A Dutch source-attribution model attributed about 19% of community carriage of ESBL E. coli to food and about 60% to human-to-human transmission (I-CHK-115), so food is a real but not the main route in the EU. Some cited studies concern pork (A-CHK-14) or only the US/China. In the US retail-meat study, chicken isolates had the lowest multidrug-resistance rate and no MRSA (A-CHK-01).
4. Apa yang masih belum jelas?
The share of human resistant infections attributable to poultry consumption versus human antibiotic use.
5. Studi mana yang mendukungnya?
A-CHK-02, A-CHK-03, A-CHK-05, A-CHK-07, A-CHK-08, A-CHK-11, A-CHK-15, A-CHK-17, A-CHK-19, I-CHK-01, I-CHK-04, I-CHK-09, I-CHK-13, I-CHK-116, I-CHK-117, I-CHK-118, I-RES-101; A-CHK-01 (limited).
6. Studi mana yang membantahnya?
I-CHK-115 (food about 19% of community ESBL carriage in the Netherlands); A-CHK-14 (pork, no difference conventional vs antibiotic-free).
7. Apa yang berlaku untuk Jerman dan Eropa?
EU: growth promoters banned since 2006; harmonised AMR monitoring shows resistance varies greatly by country, with encouraging downward trends in key indicators in several Member States over 7 years (I-CHK-04). Increasing resistance to critically important antimicrobials in poultry-associated Salmonella and Campylobacter from humans was observed in at least half of reporting countries.
8. Apa yang diketahui tentang Mesir?
Egyptian broiler studies report high multidrug resistance in Salmonella (76.7% of isolates in one province, I-CHK-09), frequent antibiotic residues above MRLs in chicken tissues (I-CHK-12), and colistin resistance (I-CHK-13). This suggests the concern is more relevant for Egypt than for the EU, but national surveillance data were not reviewed.
9. Kesimpulan praktis apa yang tepat?
Resistansi antibiotik melalui unggas adalah masalah One Health yang nyata; masalah ini ditangani melalui penggunaan yang bijak, regulasi, dan kebersihan dapur (bakteri resistan mati karena pemasakan seperti bakteri lainnya).
Rincian penilaian
- Alasan tingkat kepastian bukti
Consistent microbiological and molecular evidence (shared ESBL genes/plasmids/strains in Dutch chicken and patients; mcr-1 in Chinese animals, meat and patients; FQ-resistant Campylobacter linked to poultry) plus a systematic review showing that restricting antibiotic use lowers resistance in animals and, with less evidence, in humans. Population-level attribution of human infections to poultry is less certain.
- Kualitas sumber
Archive editorial with accurately cited, mostly high-quality studies; some (MRSA in pork, A-CHK-14) concern pork, not chicken.
- Keteralihan ke wilayah lain
- Pengecualian individual
Risk is higher for people with direct animal contact (farmers, slaughterhouse workers).
- Cakupan wilayah klaim
- bergantung pada kondisi produksi
- Terakhir ditinjau
- 26 Oktober 2026 sementara
Bukti ilmiah secara rinci
Benar hanya dalam kondisi tertentu – Klaim ini hanya berlaku untuk dosis, kelompok orang, cara pengolahan, atau keadaan tertentu.
Pertanyaan penelitian: Does antibiotic use in poultry production select resistant bacteria (ESBL E. coli, resistant Campylobacter/Salmonella, mcr-1) that reach humans through the food chain, and how large is this contribution?
Pertanyaan penelitian secara rinci (PECO)
- Populasi
- Consumers and general population
- Intervensi atau paparan
- Antibiotic use in poultry; consumption/handling of poultry meat
- Pembanding
- Lower or restricted antibiotic use; other sources of resistance
- Cakupan geografis
- production-dependent (country-specific use and regulation)
- Luaran
- resistant bacteria in meat
- human carriage/infection with poultry-associated resistant strains
- attributable fraction
Hasil studi sebagaimana dilaporkan oleh para penulis. Penilaian kami menyusul di bawah.
Apa yang mendukung klaim ini?
Less antibiotics in farm animals, less resistance
Tang KL et al.. Lancet Planet Health 2017 · PMID 29387833 · DOI 10.1016/S2542-5196(17)30141-9 Meta-analisisteks lengkap, penilaian risiko bias terstrukturSystematic review/meta-analysis of interventions restricting antibiotic use in food animals.
- Hasil sebenarnya
- Resistance in animals reduced (pooled risk differences mostly -0.10 to -0.15); in humans about 24% lower prevalence, stronger with animal contact.
- Kualitas metodologis
- moderate (SR of mostly observational studies)
- Relevansi
- direct
- Keterbatasan
- Human evidence thinner than animal evidence.
Same resistance genes in Dutch chicken and patients
Leverstein-van Hall MA et al.. Clin Microbiol Infect 2011 · PMID 21463397 · DOI 10.1111/j.1469-0691.2011.03497.x Studi potong lintangabstrak diperiksaDutch genotyping of ESBL genes in retail chicken and patients.
- Hasil sebenarnya
- 94% of retail chicken with ESBL producers; 35% of human isolates with poultry-associated ESBL genes; 19% on plasmids indistinguishable from poultry.
- Kualitas metodologis
- moderate (molecular epidemiology)
- Relevansi
- direct
- Keterbatasan
- Shared genes do not prove direction or share of transmission.
EU report 2023-2024: resistant bacteria from poultry still common
EFSA and ECDC. EFSA J 2026 · DOI 10.2903/j.efsa.2026.9887 Studi pengukuran / residuabstrak diperiksabaru ditambahkanEU AMR summary report 2023-2024.
- Hasil sebenarnya
- Rising ciprofloxacin resistance in poultry-associated Salmonella and C. jejuni from humans in more than half of reporting countries; large country differences.
- Kualitas metodologis
- high (harmonised surveillance)
- Relevansi
- direct
- Keterbatasan
- Abstract only.
Apa yang menentang klaim ini?
Most resistant gut bacteria in Dutch people come from other people, about one fifth from food
Mughini-Gras L et al.. Lancet Planet Health 2019 · PMID 31439317 · DOI 10.1016/S2542-5196(19)30130-5 Kajian risikoabstrak diperiksabaru ditambahkanDutch source-attribution model for community ESBL/pAmpC E. coli carriage.
- Hasil sebenarnya
- Human-to-human 60.1% (40.0-73.5); food 18.9% (7.0-38.3); farm animals non-occupational 3.6%.
- Kualitas metodologis
- moderate (large dataset, model assumptions)
- Relevansi
- direct; limits the size of the food route
- Keterbatasan
- Wide uncertainty; Netherlands only.
MRSA in US retail pork
O'Brien AM et al.. PLoS One 2012 · PMID 22276147 · DOI 10.1371/journal.pone.0030092 Studi potong lintangabstrak diperiksaRetail pork MRSA comparison.
- Hasil sebenarnya
- No difference between conventional and alternative pork.
- Kualitas metodologis
- low-moderate
- Relevansi
- indirect (pork)
- Keterbatasan
- Not poultry.
Apa kata bukti secara keseluruhan?
Penilaian redaksi berdasarkan studi di atas – bukan hasil studi itu sendiri.
Posisi mana yang lebih didukung?
Antibiotic use in poultry contributes to resistant bacteria reaching humans, but in the EU food is a minority source of community carriage; the problem is larger where use is routine and unregulated, as reported for Egypt.
Mengapa sebagian studi lebih berbobot
Surveillance (I-CHK-116), molecular studies (A-CHK-02/03, A-CHK-11) and an intervention meta-analysis (I-CHK-01) consistently support the pathway; attribution modelling (I-CHK-115) quantifies a moderate share. Egyptian survey data (I-CHK-117) show routine non-therapeutic use including colistin.
Apakah hubungan sebab-akibat sudah terbukti? Ya, terbukti Selection of resistance by use, shared strains/genes, and decreases after restriction together establish the pathway; magnitude varies.
Ketidakpastian yang tersisa
Share of human resistant infections attributable to poultry in Egypt; national Egyptian AMU and AMR data are lacking.
Kesimpulan yang dapat dibenarkan
Largely correct; 'routine antibiotics' describes Egypt and other countries but not legal EU practice, and food is not the main source of resistance carriage in the EU.
Mengapa studi-studi tampak saling bertentangan?
Apakah ini bergantung pada negara?
- Efek biologis umum
- Selection of resistance is universal.
- Kebiasaan makan
- Kitchen hygiene and cooking reduce transmission.
- Asal makanan
- Imported meat can carry higher resistance (I-CHK-116: imported broiler meat).
- Cemaran
- Resistant bacteria are killed by cooking like susceptible ones.
- Kondisi produksi nasional
- Egypt: all surveyed farms use antimicrobials, 65% non-therapeutically, half use colistin (I-CHK-117).
- Aturan hukum
- EU: growth promoters banned since 2006, Reg. 2019/6 restricts prophylaxis; Egypt: no GOVS decision on growth promoters found (the project's research files).
- Data pemantauan sebenarnya
- EU harmonised AMR monitoring (I-CHK-116); Egypt: no national AMU/AMR data found.
Perbedaan antarwilayah didukung oleh data yang kuat.
Pemeriksaan ulang statistik
- Plausibility of attribution shares – Shares sum to about 100% (60.1+6.9+18.9+7.9+3.6+2.6 = 100.0); credible intervals wide. tidak dapat dihitung ulang dari data yang dipublikasikan
Kepastian bukti secara keseluruhan (GRADE, disederhanakan)
- Luaran utama
- Transmission of poultry-associated resistant bacteria to humans
- Tingkat awal
- rendah (studi observasional)
- Alasan peningkatan tingkat
- consistency across molecular, surveillance and intervention data
- dose-response (restriction reduces resistance)
- Hasil
- sedang
Penilaian sederhana oleh satu penilai, mengikuti pendekatan GRADE; bukan panel GRADE formal. GRADE menilai kumpulan bukti untuk satu luaran, bukan studi individual.
Pedoman klinis dan pernyataan resmi yang diperiksa
- WHO: WHO guidelines on use of medically important antimicrobials in food-producing animals (summary, Aidara-Kane et al. 2018, PMID 29375825) (2017) · Publikasi asli
Complete restriction of antimicrobial use for growth promotion and for prevention in healthy animals; reduce overall use of medically important antimicrobials. - EFSA/ECDC: EU Summary Report on AMR in zoonotic and indicator bacteria 2023-2024 (I-CHK-116) (2026) · Publikasi asli
High resistance to common antimicrobials in Salmonella and Campylobacter; increasing ciprofloxacin resistance in poultry-associated Salmonella and C. jejuni from humans in more than half of reporting countries; country differences large.
Strategi penelusuran
Penelusuran literatur yang terdokumentasi untuk tinjauan ini (string pencarian dalam sintaksis asli basis data).
| Basis data | Tanggal | Penelusuran | Mencari | Hasil | Disertakan |
|---|---|---|---|---|---|
| Europe PMC | 26 Oktober 2026 | (TITLE:ESBL OR TITLE:"extended-spectrum") AND (TITLE:attribution OR TITLE:"attributable") | kedua arah | 4 | |
| PubMed | 26 Oktober 2026 | (ESBL[tiab] OR extended-spectrum[tiab]) AND (attribut*[ti]) AND (food[tiab] OR chicken[tiab]) | bukti yang menentang | 3 | |
| Europe PMC | 26 Oktober 2026 | TITLE:"European Union summary report on antimicrobial resistance" AND PUB_YEAR:[2025 TO 2026] | bukti pendukung | 3 | |
| Crossref | 26 Oktober 2026 | query.title=European Union summary report on antimicrobial resistance zoonotic indicator bacteria 2023-2024 | bukti pendukung | 5 | |
| Europe PMC | 26 Oktober 2026 | TITLE:"WHO guidelines on use of medically important antimicrobials in food-producing animals" | pedoman | 3 | |
| the project's research files (EG vet_drugs, RS-EG-41) then PubMed efetch | 26 Oktober 2026 | Egyptian antimicrobial use survey | bukti pendukung | 1 |
Pertanyaan terbuka
National Egyptian AMU and resistance surveillance; attribution of resistant infections in Egypt.
Seberapa mendalam ini diperiksa?
22 studi terkait: 7 diperiksa dalam teks lengkap (5 di antaranya dengan penilaian risiko bias terstruktur), 15 berdasarkan abstrak, 0 hanya secara bibliografis. Belum ada penilaian formal oleh dua penilai independen dan belum ada tinjauan pakar manusia yang independen.
Tinjauan ilmiah terakhir: 26 Oktober 2026
Riwayat penilaian
- 25 Oktober 2026 · Fase 1 · Penilaian awal: Sebagian besar benar (sedang)
- 26 Oktober 2026 · Fase 4 (tinjauan bukti sistematis) · Diperiksa ulang dengan bukti yang diperluas; penilaian tidak berubah: Sebagian besar benar (sedang)
New EU surveillance, WHO guideline and Egyptian use data strengthen the pathway; Dutch attribution modelling limits the size of the food route. Verdict and certainty unchanged.
Sumber baru: I-CHK-115 I-CHK-116 I-CHK-117 I-CHK-118
Dalam bahasa sederhana
Arsip menyatakan bahwa ayam diberi banyak antibiotik dan bahwa bakteri resistan dapat berpindah dari ayam ke manusia. Hal ini sebagian besar didukung oleh bukti: studi di Belanda menemukan gen resistansi yang sama pada daging ayam dan pada pasien, dan negara-negara yang membatasi antibiotik pada hewan melihat resistansi yang lebih rendah. Uni Eropa telah melarang antibiotik sebagai pemacu pertumbuhan sejak 2006, sementara studi dari Mesir menunjukkan tingkat resistansi dan residu obat yang tinggi pada ayam. Pemasakan yang benar dan kebersihan dapur mengurangi risiko bagi konsumen.
Studi tentang klaim ini
Studi yang mendukung klaim (18)
-
Resistant Staphylococcus on US meat
Waters AE et al.. Clin Infect Dis 2011 · PMID 21498385 · DOI 10.1093/cid/cir181Studi potong lintangdikutip oleh arsip Tayebatteks lengkap, penilaian risiko bias terstruktur★ studi kunciAlmost half of meat samples carried S. aureus; about half of the isolates were multidrug-resistant, but for chicken it was about a quarter and no MRSA was found on chicken.
Apakah studi ini mendukung klaim spesifik tersebut? Ya · Kualitas metodologis: sedang · Tingkat kepastian bukti: lihat penilaian keseluruhan atas klaim
Publikasi asli · Rincian ilmiah
Penjelasan studi secara sederhana
- Apa yang ingin diketahui para peneliti?
What are the prevalence, resistance and genotypes of S. aureus in US meat and poultry?
- Bagaimana studi ini dilakukan?
Cross-sectional microbiological survey of retail meat and poultry with susceptibility testing and genotyping
- Berapa banyak orang, hewan, atau sampel yang diteliti?
136 samples; Retail meat and poultry samples
- Apa yang sebenarnya ditemukan?
S. aureus: turkey 77%, pork 42%, chicken 41%, beef 37%; multidrug resistance 52% overall (chicken 26%); MRSA 3 isolates, none from chicken.
- Seberapa besar efek yang teramati?
Proportions; comparisons between sample types
- Apa arti hasilnya dalam kehidupan sehari-hari?
Raw meat can carry resistant bacteria; hygiene and cooking matter.
- Apa keterbatasan studi ini?
Small convenience sample; mixed meats; no human outcomes; funded by an advocacy foundation; authors say public-health relevance is unclear.
- Apa yang dikatakannya tentang klaim spesifik Elawady?
Supports presence of resistant bacteria on meat.
- Apakah hasilnya berlaku untuk Jerman dan Eropa?
Moderate; EU AMR monitoring covers MRSA.
- Apa yang secara tegas tidak dapat disimpulkan dari studi ini?
Cannot show how many people get sick.
-
Same resistance genes in Dutch chicken and patients
Leverstein-van Hall MA et al.. Clin Microbiol Infect 2011 · PMID 21463397 · DOI 10.1111/j.1469-0691.2011.03497.xStudi potong lintangdikutip oleh arsip Tayebatabstrak diperiksa★ studi kunciMost retail chicken had ESBL bacteria, and many human isolates shared the same genes and plasmids.
Apakah studi ini mendukung klaim spesifik tersebut? Ya · Kualitas metodologis: tinggi · Tingkat kepastian bukti: lihat penilaian keseluruhan atas klaim
Publikasi asli · Rincian ilmiah
Penjelasan studi secara sederhana
- Apa yang ingin diketahui para peneliti?
What proportion of human clinical ESBL E. coli carry poultry-associated genes, plasmids and strains?
- Bagaimana studi ini dilakukan?
Molecular epidemiological study comparing ESBL genes, plasmids and strains from poultry, retail chicken and human clinical isolates
- Berapa banyak orang, hewan, atau sampel yang diteliti?
98 retail chicken samples; 516 human clinical samples; Retail chicken, poultry, human clinical samples from 31 labs
- Apa yang sebenarnya ditemukan?
94% of retail meat samples contained ESBL producers; 39% of these belonged to E. coli genotypes also present in human samples. 35% of human isolates contained poultry-associated ESBL genes; 19% had PA genes on IncI1 plasmids indistinguishable from poultry.
- Seberapa besar efek yang teramati?
Descriptive proportions; microarray, pMLST, MLST
- Apa arti hasilnya dalam kehidupan sehari-hari?
Resistance genes can move from poultry to people.
- Apa keterbatasan studi ini?
Cross-sectional; direction of transmission inferred; 2009 data
- Apa yang dikatakannya tentang klaim spesifik Elawady?
Supports the claim.
- Apakah hasilnya berlaku untuk Jerman dan Eropa?
High (EU country).
- Apa yang secara tegas tidak dapat disimpulkan dari studi ini?
Cannot say how many human infections come from chicken.
-
ESBL genes in Dutch chicken meat and people
Overdevest I et al.. Emerg Infect Dis 2011 · PMID 21762575 · DOI 10.3201/eid1707.110209Studi potong lintangdikutip oleh arsip Tayebatabstrak diperiksaFour in five chicken samples had ESBL genes, matching those found in people.
Apakah studi ini mendukung klaim spesifik tersebut? Ya · Kualitas metodologis: sedang · Tingkat kepastian bukti: lihat penilaian keseluruhan atas klaim
Publikasi asli · Rincian ilmiah
Penjelasan studi secara sederhana
- Apa yang ingin diketahui para peneliti?
What are prevalence and characteristics of ESBL genes in retail chicken and humans in the Netherlands?
- Bagaimana studi ini dilakukan?
Cross-sectional study of ESBL genes in retail chicken and human rectal/blood isolates
- Berapa banyak orang, hewan, atau sampel yang diteliti?
Not stated in abstract; Retail chicken; patients in 4 hospitals
- Apa yang sebenarnya ditemukan?
ESBL genes in 79.8% of chicken meat; predominant genes identical in meat and human rectal swabs; frequently in blood isolates; high similarity of E. coli strains.
- Seberapa besar efek yang teramati?
Descriptive
- Apa arti hasilnya dalam kehidupan sehari-hari?
Resistant bacteria on raw chicken are common in some countries.
- Apa keterbatasan studi ini?
Directionality inferred; Sample sizes not in abstract
- Apa yang dikatakannya tentang klaim spesifik Elawady?
Supports the claim.
- Apakah hasilnya berlaku untuk Jerman dan Eropa?
High.
- Apa yang secara tegas tidak dapat disimpulkan dari studi ini?
Cannot prove transmission direction.
-
Global antibiotic use in farm animals
Van Boeckel TP et al.. Proc Natl Acad Sci U S A 2015 · PMID 25792457 · DOI 10.1073/pnas.1503141112Lainnyadikutip oleh arsip Tayebatabstrak diperiksa★ studi kunciModels estimated about 63,000 tons used in 2010 with a projected 67% increase by 2030.
Apakah studi ini mendukung klaim spesifik tersebut? Ya · Kualitas metodologis: sedang · Tingkat kepastian bukti: lihat penilaian keseluruhan atas klaim
Publikasi asli · Rincian ilmiah
Penjelasan studi secara sederhana
- Apa yang ingin diketahui para peneliti?
How much antimicrobial is used in livestock globally and how will it change?
- Bagaimana studi ini dilakukan?
Bayesian modelling of global antimicrobial use in food animals for 2010 and 2030
- Berapa banyak orang, hewan, atau sampel yang diteliti?
Not applicable; Global livestock (cattle, chicken, pigs)
- Apa yang sebenarnya ditemukan?
Average 45 (cattle), 148 (chicken), 172 (pigs) mg/kg. Increase of 67% from 63,151 +/- 1,560 t to 105,596 +/- 3,605 t (2010-2030). Up to a third of increase from middle-income countries shifting to intensive systems; BRICS +99%.
- Seberapa besar efek yang teramati?
Bayesian models
- Apa arti hasilnya dalam kehidupan sehari-hari?
Antibiotic use in farming is large and growing in middle-income countries.
- Apa keterbatasan studi ini?
Extrapolation from high-income data; Model uncertainty larger than reported SD may suggest
- Apa yang dikatakannya tentang klaim spesifik Elawady?
Supports the context of the claim.
- Apakah hasilnya berlaku untuk Jerman dan Eropa?
Moderate.
- Apa yang secara tegas tidak dapat disimpulkan dari studi ini?
Cannot show use in a given country.
-
Resistant Campylobacter linked to poultry in the US
Kassenborg HD et al.. Clin Infect Dis 2004 · PMID 15095200 · DOI 10.1086/381597Studi kasus-kontroldikutip oleh arsip Tayebatabstrak diperiksaDomestic resistant infections were linked to eating chicken or turkey at restaurants.
Apakah studi ini mendukung klaim spesifik tersebut? Ya · Kualitas metodologis: sedang · Tingkat kepastian bukti: lihat penilaian keseluruhan atas klaim
Publikasi asli · Rincian ilmiah
Penjelasan studi secara sederhana
- Apa yang ingin diketahui para peneliti?
What are risk factors for fluoroquinolone-resistant Campylobacter infection?
- Bagaimana studi ini dilakukan?
Population-based case-control study (FoodNet)
- Berapa banyak orang, hewan, atau sampel yang diteliti?
858 isolates tested; 64 FQ-resistant vs 582 susceptible with travel data; 33 matched case-control pairs; Patients with Campylobacter infection and matched controls
- Apa yang sebenarnya ditemukan?
11% resistant. Travel OR 7.6 (4.3-13.4). Domestic cases: eating chicken or turkey at commercial establishment matched OR 10.0 (1.3-78).
- Seberapa besar efek yang teramati?
OR, matched OR
- Apa arti hasilnya dalam kehidupan sehari-hari?
Poultry can transmit resistant Campylobacter.
- Apa keterbatasan studi ini?
Very wide CI (only 33 pairs); Recall bias
- Apa yang dikatakannya tentang klaim spesifik Elawady?
Supports.
- Apakah hasilnya berlaku untuk Jerman dan Eropa?
Moderate.
- Apa yang secara tegas tidak dapat disimpulkan dari studi ini?
Precise risk size.
-
US ban of fluoroquinolones in poultry
Nelson JM et al.. Clin Infect Dis 2007 · PMID 17342653 · DOI 10.1086/512369Tinjauan naratifdikutip oleh arsip Tayebatabstrak diperiksaResistance concerns led the US to withdraw enrofloxacin from poultry in 2005.
Apakah studi ini mendukung klaim spesifik tersebut? Ya · Kualitas metodologis: sedang · Tingkat kepastian bukti: lihat penilaian keseluruhan atas klaim
Publikasi asli · Rincian ilmiah
Penjelasan studi secara sederhana
- Apa yang ingin diketahui para peneliti?
What happened after fluoroquinolones were withdrawn from US poultry?
- Bagaimana studi ini dilakukan?
Review of FQ-resistant Campylobacter and US regulatory withdrawal of enrofloxacin in poultry
- Berapa banyak orang, hewan, atau sampel yang diteliti?
Not applicable; US
- Apa yang sebenarnya ditemukan?
FDA proposed withdrawal in 2000; enrofloxacin withdrawn from poultry effective September 2005; resistant strains continue to circulate.
- Seberapa besar efek yang teramati?
Not applicable
- Apa arti hasilnya dalam kehidupan sehari-hari?
Regulators can restrict drugs that drive resistance.
- Apa keterbatasan studi ini?
Narrative; Authors from US agencies
- Apa yang dikatakannya tentang klaim spesifik Elawady?
Supports problem existence.
- Apakah hasilnya berlaku untuk Jerman dan Eropa?
Moderate.
- Apa yang secara tegas tidak dapat disimpulkan dari studi ini?
Cannot quantify impact.
-
Discovery of transferable colistin resistance (mcr-1) in China
Liu YY et al.. Lancet Infect Dis 2016 · PMID 26603172 · DOI 10.1016/S1473-3099(15)00424-7Lainnyadikutip oleh arsip Tayebatabstrak diperiksa★ studi kunciA transferable gene making bacteria resistant to the last-resort antibiotic colistin was found in animals, meat and some patients.
Apakah studi ini mendukung klaim spesifik tersebut? Ya · Kualitas metodologis: tinggi · Tingkat kepastian bukti: lihat penilaian keseluruhan atas klaim
Publikasi asli · Rincian ilmiah
Penjelasan studi secara sederhana
- Apa yang ingin diketahui para peneliti?
Is there plasmid-mediated polymyxin resistance in Enterobacteriaceae in China?
- Bagaimana studi ini dilakukan?
Surveillance plus microbiological and molecular study discovering plasmid-mediated colistin resistance (mcr-1)
- Berapa banyak orang, hewan, atau sampel yang diteliti?
804 animals; 523 raw meat samples; 1,322 inpatient samples; E. coli and K. pneumoniae from food animals, raw meat and inpatients in five provinces
- Apa yang sebenarnya ditemukan?
mcr-1 in 166/804 (21%) animals, 78/523 (15%) raw meat, 16/1322 (1%) inpatients; transferable by conjugation; negated colistin in mice.
- Seberapa besar efek yang teramati?
Descriptive; conjugation frequencies; mouse model
- Apa arti hasilnya dalam kehidupan sehari-hari?
Farm antibiotic use can threaten important human medicines.
- Apa keterbatasan studi ini?
China-specific surveillance; Index strain from a pig; poultry-specific share not given in abstract
- Apa yang dikatakannya tentang klaim spesifik Elawady?
Supports resistance concern.
- Apakah hasilnya berlaku untuk Jerman dan Eropa?
Moderate.
- Apa yang secara tegas tidak dapat disimpulkan dari studi ini?
Not specific to chicken.
-
Less resistance on farms that stopped antibiotics
Sapkota AR et al.. Environ Health Perspect 2011 · PMID 21827979 · DOI 10.1289/ehp.1003350Studi potong lintangdikutip oleh arsip Tayebatabstrak diperiksaPoultry houses that switched to organic had far fewer multidrug-resistant bacteria.
Apakah studi ini mendukung klaim spesifik tersebut? Ya · Kualitas metodologis: sedang · Tingkat kepastian bukti: lihat penilaian keseluruhan atas klaim
Publikasi asli · Rincian ilmiah
Penjelasan studi secara sederhana
- Apa yang ingin diketahui para peneliti?
Does transition to organic practices lower antibiotic-resistant Enterococcus on poultry farms?
- Bagaimana studi ini dilakukan?
Field comparison of resistant Enterococcus in conventional vs newly organic poultry houses
- Berapa banyak orang, hewan, atau sampel yang diteliti?
20 houses; 259 Enterococcus isolates; 10 conventional and 10 newly organic poultry houses
- Apa yang sebenarnya ditemukan?
MDR E. faecalis 42% conventional vs 10% organic (p=0.02); MDR E. faecium 84% vs 17% (p<0.001).
- Seberapa besar efek yang teramati?
GLMM
- Apa arti hasilnya dalam kehidupan sehari-hari?
Reducing antibiotic use reduces resistance.
- Apa keterbatasan studi ini?
Small number of houses; Farm environment, not meat
- Apa yang dikatakannya tentang klaim spesifik Elawady?
Supports.
- Apakah hasilnya berlaku untuk Jerman dan Eropa?
Moderate.
- Apa yang secara tegas tidak dapat disimpulkan dari studi ini?
Cannot show human health effect.
-
US Salmonella outbreak from one chicken company
Gieraltowski L et al.. PLoS One 2016 · PMID 27631492 · DOI 10.1371/journal.pone.0162369Laporan wabahdikutip oleh arsip Tayebatteks lengkap, penilaian risiko bias terstruktur634 people fell ill from resistant Salmonella traced to one company's chicken.
Apakah studi ini mendukung klaim spesifik tersebut? Ya · Kualitas metodologis: sedang · Tingkat kepastian bukti: lihat penilaian keseluruhan atas klaim
Publikasi asli · Rincian ilmiah
Penjelasan studi secara sederhana
- Apa yang ingin diketahui para peneliti?
What caused a large multistate MDR Salmonella Heidelberg outbreak?
- Bagaimana studi ini dilakukan?
Outbreak investigation (epidemiological, laboratory, traceback)
- Berapa banyak orang, hewan, atau sampel yang diteliti?
634 cases; 435 interviewed; 634 US case-patients
- Apa yang sebenarnya ditemukan?
634 sick (38% hospitalised, no deaths); 87% of those with brand data ate Company A chicken; 67% of tested patient isolates resistant, 35% multidrug-resistant; Salmonella in 26% of samples at the implicated plants, down to about 5% after fixes.
- Seberapa besar efek yang teramati?
Descriptive
- Apa arti hasilnya dalam kehidupan sehari-hari?
Shows why safe handling of raw chicken matters.
- Apa keterbatasan studi ini?
Single outbreak
- Apa yang dikatakannya tentang klaim spesifik Elawady?
Supports existence of hazard.
- Apakah hasilnya berlaku untuk Jerman dan Eropa?
Moderate.
- Apa yang secara tegas tidak dapat disimpulkan dari studi ini?
Cannot give routine prevalence in chicken and does not support an 80-85% contamination rate.
-
Urinary infection E. coli genes in Danish chicken and pork
Jakobsen L et al.. Int J Food Microbiol 2010 · PMID 20656368 · DOI 10.1016/j.ijfoodmicro.2010.06.025Studi potong lintangdikutip oleh arsip Tayebatabstrak diperiksaE. coli from meat had virulence genes similar to those from patients with urinary infections.
Apakah studi ini mendukung klaim spesifik tersebut? Ya · Kualitas metodologis: sedang · Tingkat kepastian bukti: lihat penilaian keseluruhan atas klaim
Publikasi asli · Rincian ilmiah
Penjelasan studi secara sederhana
- Apa yang ingin diketahui para peneliti?
Could broiler meat and pork be sources of ExPEC strains in humans?
- Bagaimana studi ini dilakukan?
Molecular comparison of ExPEC virulence genes in E. coli from UTI patients, community humans, meat and animals
- Berapa banyak orang, hewan, atau sampel yang diteliti?
964 isolates; 964 E. coli isolates
- Apa yang sebenarnya ditemukan?
Seven of eight ExPEC-related genes detected in isolates from broiler meat, broilers, pork and pigs; strong similarities between human and meat/animal isolate profiles.
- Seberapa besar efek yang teramati?
PCR; cluster analysis
- Apa arti hasilnya dalam kehidupan sehari-hari?
Meat could be one source of bacteria causing urinary infections.
- Apa keterbatasan studi ini?
Gene presence, not transmission proof
- Apa yang dikatakannya tentang klaim spesifik Elawady?
Supports plausibility.
- Apakah hasilnya berlaku untuk Jerman dan Eropa?
High.
- Apa yang secara tegas tidak dapat disimpulkan dari studi ini?
Cannot prove transmission.
-
Less antibiotics in farm animals, less resistance
Tang KL et al.. Lancet Planet Health 2017 · PMID 29387833 · DOI 10.1016/S2542-5196(17)30141-9Meta-analisispemeriksaan silang independenteks lengkap, penilaian risiko bias terstruktur★ studi kunciRestricting antibiotics in livestock reduced resistant bacteria in animals and, in fewer studies, in people.
Apakah studi ini mendukung klaim spesifik tersebut? Ya · Kualitas metodologis: tinggi · Tingkat kepastian bukti: lihat penilaian keseluruhan atas klaim
Publikasi asli · Rincian ilmiah
Penjelasan studi secara sederhana
- Apa yang ingin diketahui para peneliti?
Effect of restricting antibiotic use in food animals on resistance in animals and humans
- Bagaimana studi ini dilakukan?
Systematic review and meta-analysis (WHO-commissioned)
- Berapa banyak orang, hewan, atau sampel yang diteliti?
181 studies (179 animal, 21 human); Food-producing animals; humans
- Apa yang sebenarnya ditemukan?
In animals resistance was usually 10-15 percentage points lower with restrictions (poultry 18 points); in studied humans 24 points lower, mainly in farm workers (29 points) and much less in non-farm people (9 points, 3 studies).
- Seberapa besar efek yang teramati?
Random-effects risk differences
- Apa arti hasilnya dalam kehidupan sehari-hari?
Prudent farm antibiotic use protects human medicine.
- Apa keterbatasan studi ini?
Mostly cross-sectional, poorly adjusted studies; very high heterogeneity; few human studies, mostly farm workers; possible publication bias in human studies; almost no data from low- and middle-income countries.
- Apa yang dikatakannya tentang klaim spesifik Elawady?
Supports.
- Apakah hasilnya berlaku untuk Jerman dan Eropa?
High.
- Apa yang secara tegas tidak dapat disimpulkan dari studi ini?
Cannot quantify effect on all consumers.
-
EU report on antibiotic resistance in food animals
EFSA, ECDC. EFSA J 2024 · PMID 38419967 · DOI 10.2903/j.efsa.2024.8583Lainnyapemeriksaan silang independenabstrak diperiksaResistance in poultry-linked bacteria is common and varies by country, but key indicators improved in several countries.
Apakah studi ini mendukung klaim spesifik tersebut? Ya · Kualitas metodologis: tinggi · Tingkat kepastian bukti: lihat penilaian keseluruhan atas klaim
Publikasi asli · Rincian ilmiah
Penjelasan studi secara sederhana
- Apa yang ingin diketahui para peneliti?
AMR in Salmonella, Campylobacter, indicator E. coli, MRSA in humans, animals, food
- Bagaimana studi ini dilakukan?
EU harmonised AMR monitoring report
- Berapa banyak orang, hewan, atau sampel yang diteliti?
Not stated in abstract; EU MSs
- Apa yang sebenarnya ditemukan?
Resistance differed greatly between countries; resistance to common antimicrobials frequent in Salmonella and Campylobacter; increasing resistance to a critically important antimicrobial in poultry-associated Salmonella and Campylobacter from humans in at least half of reporting countries; encouraging progress in key outcome indicators in several MSs over 7 years.
- Seberapa besar efek yang teramati?
Descriptive; trend analysis
- Apa arti hasilnya dalam kehidupan sehari-hari?
The problem is real in the EU too, but monitored.
- Apa keterbatasan studi ini?
Country variation in sampling
- Apa yang dikatakannya tentang klaim spesifik Elawady?
Supports, with nuance.
- Apakah hasilnya berlaku untuk Jerman dan Eropa?
Directly EU.
- Apa yang secara tegas tidak dapat disimpulkan dari studi ini?
Not consumer risk per meal.
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Salmonella in Egyptian broiler chickens
Elkenany R et al.. BMC Vet Res 2019 · PMID 31029108 · DOI 10.1186/s12917-019-1867-zStudi potong lintangpemeriksaan silang independenteks lengkap, penilaian risiko bias terstrukturAbout 29% of retail chicken carcasses and 32% of farm chickens in one Egyptian province had Salmonella, mostly multidrug-resistant.
Apakah studi ini mendukung klaim spesifik tersebut? Sebagian · Kualitas metodologis: sedang · Tingkat kepastian bukti: lihat penilaian keseluruhan atas klaim
Publikasi asli · Rincian ilmiah
Penjelasan studi secara sederhana
- Apa yang ingin diketahui para peneliti?
Prevalence, resistance and virulence genes of Salmonella in broilers and retail carcasses
- Bagaimana studi ini dilakukan?
Cross-sectional microbiological survey
- Berapa banyak orang, hewan, atau sampel yang diteliti?
420 samples from 5 broiler farms and 5 retail shops, El-Sharkia, summer 2017
- Apa yang sebenarnya ditemukan?
Salmonella in 28.6% of all samples (carcasses 29.4%, cloacal swabs 32%, environment 22%); 76.7% of isolates multidrug-resistant; all resistant to trimethoprim-sulfamethoxazole; none to imipenem.
- Seberapa besar efek yang teramati?
Descriptive
- Apa arti hasilnya dalam kehidupan sehari-hari?
In Egypt, careful handling and cooking of chicken is especially important.
- Apa keterbatasan studi ini?
Only 5 farms and 5 shops in one province, one season; no human data; descriptive only.
- Apa yang dikatakannya tentang klaim spesifik Elawady?
Supports concern but not 80-85%.
- Apakah hasilnya berlaku untuk Jerman dan Eropa?
Low (Egypt).
- Apa yang secara tegas tidak dapat disimpulkan dari studi ini?
Not national.
-
Colistin resistance in the Middle East and North Africa
Saniour R et al.. Microorganisms 2026 · PMID 42655038 · DOI 10.3390/microorganisms14081693Tinjauan naratifpemeriksaan silang independenabstrak diperiksaResistance to the last-resort antibiotic colistin is reported in Egypt and other countries, including in poultry.
Apakah studi ini mendukung klaim spesifik tersebut? Ya · Kualitas metodologis: rendah · Tingkat kepastian bukti: lihat penilaian keseluruhan atas klaim
Publikasi asli · Rincian ilmiah
Penjelasan studi secara sederhana
- Apa yang ingin diketahui para peneliti?
Epidemiology of colistin resistance in MENA
- Bagaimana studi ini dilakukan?
Narrative review
- Berapa banyak orang, hewan, atau sampel yang diteliti?
Not applicable; Humans, animals, food, environment
- Apa yang sebenarnya ditemukan?
North Africa prevalence of colistin-resistant Gram-negatives: Tunisia 58.09%, Egypt 24.76%, Algeria 14.29%, Libya 2.86% (from available literature); mcr-1 predominant; resistance documented in poultry and food.
- Seberapa besar efek yang teramati?
Descriptive
- Apa arti hasilnya dalam kehidupan sehari-hari?
Farm antibiotic use matters for human medicine in Egypt too.
- Apa keterbatasan studi ini?
Narrative; heterogeneous sources
- Apa yang dikatakannya tentang klaim spesifik Elawady?
Supports.
- Apakah hasilnya berlaku untuk Jerman dan Eropa?
Low.
- Apa yang secara tegas tidak dapat disimpulkan dari studi ini?
Not precise prevalence.
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EU report 2023-2024: resistant bacteria from poultry still common
EFSA and ECDC. EFSA J 2026 · DOI 10.2903/j.efsa.2026.9887Studi pengukuran / residupemeriksaan silang independenabstrak diperiksaResistance to common antibiotics is frequent in Salmonella and Campylobacter, and ciprofloxacin resistance is rising in poultry-associated strains in humans.
Resistance in poultry-associated Salmonella and Campylobacter, including rising ciprofloxacin resistance in human cases.
Apakah studi ini mendukung klaim spesifik tersebut? Ya · Kualitas metodologis: tinggi · Tingkat kepastian bukti: lihat penilaian keseluruhan atas klaim
Publikasi asli · Rincian ilmiah
Penjelasan studi secara sederhana
- Apa yang ingin diketahui para peneliti?
What are the AMR levels and trends in Salmonella, Campylobacter and indicator E. coli from humans, food-producing animals and meat in the EU?
- Bagaimana studi ini dilakukan?
EU harmonised AMR monitoring report
- Berapa banyak orang, hewan, atau sampel yang diteliti?
EU-wide monitoring (numbers not in abstract)
- Apa yang sebenarnya ditemukan?
High proportions of Salmonella and Campylobacter isolates from humans and animals resistant to ampicillin, tetracycline and sulfonamides. Increasing ciprofloxacin resistance in human infections with a poultry-associated Salmonella serovar and in C. jejuni in more than half of reporting countries. Resistance differed greatly between countries. Very high third-generation cephalosporin resistance in Salmonella from imported broiler and turkey meat. Encouraging progress in reducing AMR in food-producing animals in several Member States over the past decade, partly plateauing.
- Seberapa besar efek yang teramati?
High proportions of Salmonella and Campylobacter isolates from humans and animals resistant to ampicillin, tetracycline and sulfonamides. Increasing ciprofloxacin resistance in human infections with a poultry-associated Salmonella serovar and in C. jejuni in more than half of reporting countries. Resistance differed greatly between countries. Very high third-generation cephalosporin resistance in Salmonella from imported broiler and turkey meat. Encouraging progress in reducing AMR in food-producing animals in several Member States over the past decade, partly plateauing.
- Apa arti hasilnya dalam kehidupan sehari-hari?
Antibiotic resistance linked to poultry is a real, monitored problem in Europe, improving in some countries.
- Apa keterbatasan studi ini?
Abstract only (read via Crossref); No PMID located
- Apa yang dikatakannya tentang klaim spesifik Elawady?
Supports the resistance part of the claim for the EU, with country differences.
- Apakah hasilnya berlaku untuk Jerman dan Eropa?
Directly EU data.
- Apa yang secara tegas tidak dapat disimpulkan dari studi ini?
Does not quantify how many human infections come from eating chicken.
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Egyptian farms report routine antibiotic use, often without medical need
ElSayed N et al.. J Egypt Public Health Assoc 2025 · PMID 39828782 · DOI 10.1186/s42506-024-00180-wStudi potong lintangpemeriksaan silang independenabstrak diperiksaAll 111 farms used antibiotics; 65% also used them for prevention or growth.
Routine and non-therapeutic antibiotic use, including colistin, reported on Egyptian farms.
Apakah studi ini mendukung klaim spesifik tersebut? Ya · Kualitas metodologis: rendah · Tingkat kepastian bukti: lihat penilaian keseluruhan atas klaim
Publikasi asli · Rincian ilmiah
Penjelasan studi secara sederhana
- Apa yang ingin diketahui para peneliti?
What antimicrobials are used on Egyptian animal farms, for what purposes, and why?
- Bagaimana studi ini dilakukan?
Cross-sectional survey of farm personnel
- Berapa banyak orang, hewan, atau sampel yang diteliti?
111 of 150 farms (74% response)
- Apa yang sebenarnya ditemukan?
All surveyed personnel reported antimicrobial use; 65% used them for non-therapeutic purposes (prevention or growth promotion). Non-therapeutic use had no impact on FCR in any farm type. Most used: penicillins 81%, macrolides 78%, tetracyclines 72%. Half used colistin; 55% of these non-therapeutically.
- Seberapa besar efek yang teramati?
All surveyed personnel reported antimicrobial use; 65% used them for non-therapeutic purposes (prevention or growth promotion). Non-therapeutic use had no impact on FCR in any farm type. Most used: penicillins 81%, macrolides 78%, tetracyclines 72%. Half used colistin; 55% of these non-therapeutically.
- Apa arti hasilnya dalam kehidupan sehari-hari?
In Egypt, routine antibiotic use in animals is common.
- Apa keterbatasan studi ini?
Self-report; Farms selected from a private platform list; Small sample
- Apa yang dikatakannya tentang klaim spesifik Elawady?
Supports 'routine antibiotics' for Egypt.
- Apakah hasilnya berlaku untuk Jerman dan Eropa?
Not applicable to the EU (growth promoters banned since 2006).
- Apa yang secara tegas tidak dapat disimpulkan dari studi ini?
Not representative of all Egyptian farms.
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WHO: stop using antibiotics to make farm animals grow
Aidara-Kane A et al.. Antimicrob Resist Infect Control 2018 · PMID 29375825 · DOI 10.1186/s13756-017-0294-9Pedoman / pernyataan sikappemeriksaan silang independenabstrak diperiksaWHO recommends ending antibiotic use for growth promotion and for prevention in healthy animals.
WHO states antimicrobial use in food animals selects for resistance transmissible to humans and recommends ending growth promotion.
Apakah studi ini mendukung klaim spesifik tersebut? Ya · Kualitas metodologis: tinggi · Tingkat kepastian bukti: lihat penilaian keseluruhan atas klaim
Publikasi asli · Rincian ilmiah
Penjelasan studi secara sederhana
- Apa yang ingin diketahui para peneliti?
How should medically important antimicrobials be used in food-producing animals?
- Bagaimana studi ini dilakukan?
Summary of WHO guideline developed with GRADE and commissioned systematic reviews
- Berapa banyak orang, hewan, atau sampel yang diteliti?
not applicable
- Apa yang sebenarnya ditemukan?
Recommends reduction in overall use of medically important antimicrobials, complete restriction of use for growth promotion and for disease prevention in healthy animals, and no use of critically important antimicrobials unless susceptibility testing shows they are the only option.
- Seberapa besar efek yang teramati?
Recommends reduction in overall use of medically important antimicrobials, complete restriction of use for growth promotion and for disease prevention in healthy animals, and no use of critically important antimicrobials unless susceptibility testing shows they are the only option.
- Apa arti hasilnya dalam kehidupan sehari-hari?
The international health authority agrees that farm antibiotic use is a resistance problem.
- Apa keterbatasan studi ini?
Recommendations rest partly on low-certainty evidence
- Apa yang dikatakannya tentang klaim spesifik Elawady?
Supports the resistance concern; does not quantify human harm.
- Apakah hasilnya berlaku untuk Jerman dan Eropa?
EU rules (Reg. 2019/6) largely implement these principles.
- Apa yang secara tegas tidak dapat disimpulkan dari studi ini?
Not a measure of current use in any country.
-
Gentamicin found in one in five Egyptian chicken samples, mostly in liver
Kamouh HM et al.. Open Vet J 2024 · PMID 38633178 · DOI 10.5455/OVJ.2024.v14.i1.40Studi pengukuran / residupemeriksaan silang independenteks lengkap diperiksa★ studi kunci21% of samples contained gentamicin, most often liver and gizzard; boiling removed over 90%.
Residues of several antibiotics in Egyptian chicken indicate frequent use.
Apakah studi ini mendukung klaim spesifik tersebut? Sebagian · Kualitas metodologis: rendah · Tingkat kepastian bukti: lihat penilaian keseluruhan atas klaim
Publikasi asli · Rincian ilmiah
Penjelasan studi secara sederhana
- Apa yang ingin diketahui para peneliti?
How often are oxytetracycline, gentamicin and ciprofloxacin residues present in retail chicken in Egypt, and does boiling reduce them?
- Bagaimana studi ini dilakukan?
Cross-sectional residue survey (microbial inhibition test plus HPLC) with a boiling experiment
- Berapa banyak orang, hewan, atau sampel yang diteliti?
100 samples (25 per tissue)
- Apa yang sebenarnya ditemukan?
Positive: oxytetracycline 23%, gentamicin 21%, ciprofloxacin 17% of samples. Gentamicin by tissue: breast 16%, thigh 16%, gizzard 20%, liver 32%; mean concentrations (ng/g) 31.8, 52.5, 201.3, 243.2 (max liver 378.5). Above the MRL used: breast 1/25, thigh 2/25, gizzard 4/25, liver 5/25. Boiling 30 min reduced gentamicin by 91.8-95.2% (liver 378.5 -> 18.3 ng/g), oxytetracycline by 88.2% and ciprofloxacin by 23-31%.
- Seberapa besar efek yang teramati?
Positive: oxytetracycline 23%, gentamicin 21%, ciprofloxacin 17% of samples. Gentamicin by tissue: breast 16%, thigh 16%, gizzard 20%, liver 32%; mean concentrations (ng/g) 31.8, 52.5, 201.3, 243.2 (max liver 378.5). Above the MRL used: breast 1/25, thigh 2/25, gizzard 4/25, liver 5/25. Boiling 30 min reduced gentamicin by 91.8-95.2% (liver 378.5 -> 18.3 ng/g), oxytetracycline by 88.2% and ciprofloxacin by 23-31%.
- Apa arti hasilnya dalam kehidupan sehari-hari?
Antibiotic traces are real in Egyptian chicken, especially in offal; cooking removes most gentamicin; the amounts are tiny compared with medical doses.
- Apa keterbatasan studi ini?
Small sample from one governorate; Gentamicin MRLs taken from EU bovine/porcine values (EU 37/2010 lists gentamicin MRLs only for bovine and porcine species, I-RES-01); Inconsistent counts (21 MIT-positive vs 25 positive in Table 7 text); No dietary risk assessment
- Apa yang dikatakannya tentang klaim spesifik Elawady?
Supports that gentamicin is used in Egyptian broilers; does not support kidney or hearing damage.
- Apakah hasilnya berlaku untuk Jerman dan Eropa?
Not applicable to EU production.
- Apa yang secara tegas tidak dapat disimpulkan dari studi ini?
Cannot show any health effect.
Tidak ada studi dalam kelompok ini yang ditandai sebagai studi kunci.
Studi yang membantah atau membatasi klaim (2)
-
MRSA in US retail pork
O'Brien AM et al.. PLoS One 2012 · PMID 22276147 · DOI 10.1371/journal.pone.0030092Studi potong lintangdikutip oleh arsip Tayebatabstrak diperiksaPork raised without antibiotics carried MRSA as often as conventional pork.
Apakah studi ini mendukung klaim spesifik tersebut? Tidak · Kualitas metodologis: sedang · Tingkat kepastian bukti: lihat penilaian keseluruhan atas klaim
Publikasi asli · Rincian ilmiah
Penjelasan studi secara sederhana
- Apa yang ingin diketahui para peneliti?
What is S. aureus/MRSA prevalence in conventional vs alternative retail pork?
- Bagaimana studi ini dilakukan?
Cross-sectional retail survey of S. aureus and MRSA in pork
- Berapa banyak orang, hewan, atau sampel yang diteliti?
395 pork samples; Retail pork from 36 stores
- Apa yang sebenarnya ditemukan?
S. aureus 64.8%; MRSA 6.6% (4.3-9.5%); no significant differences between conventional and alternative pork.
- Seberapa besar efek yang teramati?
Proportions, 95% CI
- Apa arti hasilnya dalam kehidupan sehari-hari?
Not about chicken.
- Apa keterbatasan studi ini?
Pork, not poultry
- Apa yang dikatakannya tentang klaim spesifik Elawady?
Limits the claim.
- Apakah hasilnya berlaku untuk Jerman dan Eropa?
Moderate.
- Apa yang secara tegas tidak dapat disimpulkan dari studi ini?
Says nothing about chicken.
-
EU ban on antibiotic growth promoters
European Parliament and Council. Official Journal of the EU (copy at legislation.gov.uk) 2003Pedoman / pernyataan sikappemeriksaan silang independenteks lengkap diperiksaSince 2006, antibiotics may not be used as growth-promoting feed additives in the EU.
Apakah studi ini mendukung klaim spesifik tersebut? Tidak · Kualitas metodologis: tidak berlaku · Tingkat kepastian bukti: lihat penilaian keseluruhan atas klaim
Publikasi asli · Rincian ilmiah
Penjelasan studi secara sederhana
- Apa yang ingin diketahui para peneliti?
Rules for feed additives including phase-out of antibiotic growth promoters
- Bagaimana studi ini dilakukan?
EU regulation
- Berapa banyak orang, hewan, atau sampel yang diteliti?
Not applicable; EU animal feed
- Apa yang sebenarnya ditemukan?
Article 11(2): antibiotics, other than coccidiostats and histomonostats, may be marketed and used as feed additives only until 31 December 2005; from 1 January 2006 deleted from the Register. Recital 25 cites the Scientific Steering Committee: growth-promoting antimicrobials from classes used in medicine should be phased out.
- Seberapa besar efek yang teramati?
Not applicable
- Apa arti hasilnya dalam kehidupan sehari-hari?
"Routine antibiotics for growth" is not legal in the EU.
- Apa keterbatasan studi ini?
Therapeutic and prophylactic veterinary use regulated separately (not covered)
- Apa yang dikatakannya tentang klaim spesifik Elawady?
Limits the claim for the EU.
- Apakah hasilnya berlaku untuk Jerman dan Eropa?
Directly EU.
- Apa yang secara tegas tidak dapat disimpulkan dari studi ini?
Does not cover therapeutic use.
Tidak ada studi dalam kelompok ini yang ditandai sebagai studi kunci.
Studi dengan hasil campuran atau tidak jelas (2)
-
Antibiotic residues in Egyptian chicken
Noah SM et al.. Sci Rep 2026 · PMID 42527435 · DOI 10.1038/s41598-026-63227-2Studi pengukuran / residupemeriksaan silang independenteks lengkap, penilaian risiko bias terstruktur★ studi kunciMany chicken samples had antibiotic residues above legal limits, especially in liver, but estimated health risk was low.
Apakah studi ini mendukung klaim spesifik tersebut? Sebagian · Kualitas metodologis: sedang · Tingkat kepastian bukti: lihat penilaian keseluruhan atas klaim
Publikasi asli · Rincian ilmiah
Penjelasan studi secara sederhana
- Apa yang ingin diketahui para peneliti?
Antibiotic residues in chicken tissues and consumer risk
- Bagaimana studi ini dilakukan?
Cross-sectional residue survey (HPLC) with risk assessment
- Berapa banyak orang, hewan, atau sampel yang diteliti?
180 samples (60 breast, 60 thigh, 60 liver); Chicken tissues from poultry shops
- Apa yang sebenarnya ditemukan?
Detected: enrofloxacin 51.67%, oxytetracycline 71.67%, sulfadimidine 16.67%; of positives, 54.84%, 55.81% and 70% exceeded MRLs. Liver had highest levels (e.g., oxytetracycline mean 10,625 ug/kg). EDI 0.012-0.590 ug/kg bw/day; HQ 0.0002-0.050, indicating no significant health risk.
- Seberapa besar efek yang teramati?
Descriptive; HQ
- Apa arti hasilnya dalam kehidupan sehari-hari?
Withdrawal periods are not always respected in some Egyptian supply chains.
- Apa keterbatasan studi ini?
One city; unclear shop selection; no confirmatory LC-MS/MS; risk estimate uses average levels and intakes only; eggs not studied.
- Apa yang dikatakannya tentang klaim spesifik Elawady?
Supports residue concern in Egypt; not toxicity.
- Apakah hasilnya berlaku untuk Jerman dan Eropa?
Low (Egypt).
- Apa yang secara tegas tidak dapat disimpulkan dari studi ini?
Cannot generalise nationwide.
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Most resistant gut bacteria in Dutch people come from other people, about one fifth from food
Mughini-Gras L et al.. Lancet Planet Health 2019 · PMID 31439317 · DOI 10.1016/S2542-5196(19)30130-5Kajian risikopemeriksaan silang independenabstrak diperiksa★ studi kunciFood accounted for about 19% of community carriage of ESBL E. coli; human-to-human spread for about 60%.
Food contributes (about 19%), but human-to-human spread dominates; limits the size of the poultry route.
Apakah studi ini mendukung klaim spesifik tersebut? Sebagian · Kualitas metodologis: sedang · Tingkat kepastian bukti: lihat penilaian keseluruhan atas klaim
Publikasi asli · Rincian ilmiah
Penjelasan studi secara sederhana
- Apa yang ingin diketahui para peneliti?
What proportion of community-acquired ESBL/pAmpC E. coli carriage is attributable to human, animal, food and environmental sources?
- Bagaimana studi ini dilakukan?
Population-based source-attribution modelling (ESBL/pAmpC genes), Netherlands 2005-2017
- Berapa banyak orang, hewan, atau sampel yang diteliti?
1,220 human and 6,275 non-human gene occurrences
- Apa yang sebenarnya ditemukan?
Human-to-human transmission within/between households 60.1% (95% CrI 40.0-73.5); secondary transmission from high-risk groups 6.9%; food 18.9% (7.0-38.3); companion animals 7.9%; farm animals (non-occupational) 3.6%; environment 2.6%. R0 for intracommunity transmission 0.63.
- Seberapa besar efek yang teramati?
Human-to-human transmission within/between households 60.1% (95% CrI 40.0-73.5); secondary transmission from high-risk groups 6.9%; food 18.9% (7.0-38.3); companion animals 7.9%; farm animals (non-occupational) 3.6%; environment 2.6%. R0 for intracommunity transmission 0.63.
- Apa arti hasilnya dalam kehidupan sehari-hari?
Food is a real but not the main route for these resistant bacteria in the Netherlands.
- Apa keterbatasan studi ini?
Model assumptions; Food not split by type in abstract; Erratum published
- Apa yang dikatakannya tentang klaim spesifik Elawady?
Supports the food-chain route but limits its size.
- Apakah hasilnya berlaku untuk Jerman dan Eropa?
Directly EU-relevant (Netherlands).
- Apa yang secara tegas tidak dapat disimpulkan dari studi ini?
Not specific to chicken; different in high-use countries.
Tidak ada studi dalam kelompok ini yang ditandai sebagai studi kunci.
Konteks wilayah
Jerman / UE
EU: growth promoters banned since 2006; harmonised AMR monitoring shows resistance varies greatly by country, with encouraging downward trends in key indicators in several Member States over 7 years (I-CHK-04). Increasing resistance to critically important antimicrobials in poultry-associated Salmonella and Campylobacter from humans was observed in at least half of reporting countries.
Mesir
Egyptian broiler studies report high multidrug resistance in Salmonella (76.7% of isolates in one province, I-CHK-09), frequent antibiotic residues above MRLs in chicken tissues (I-CHK-12), and colistin resistance (I-CHK-13). This suggests the concern is more relevant for Egypt than for the EU, but national surveillance data were not reviewed.
- Food-safety governance and official controls
- Pesticide residues in fruit and vegetables on the EU/German market (incl. imports from Egypt)
- Pesticide residues in produce sold on the Egyptian domestic market
- Antibiotic (veterinary drug) residues in poultry meat and eggs
- Antimicrobial use in food animals and antibiotic growth promoters
- Hormones in poultry, meat, milk and farmed fish
- Salmonella in laying hens, eggs and broiler chicken
- Dioxins, PCBs and PFAS in eggs and other animal foods
- Aflatoxin M1 in milk and dairy products
- Aflatoxins in groundnuts (peanuts)
- Heavy metals in fish
- Farmed fish (aquaculture): drugs, water source and controls
- Import controls and the meaning of RASFF notifications for Egyptian products
Apa yang berlaku di negara saya?
Penilaian ilmiah umum
Sebagian besar benar Penggunaan antibiotik pada unggas memang ikut berperan dalam sampainya bakteri resistan ke manusia; besarnya masalah sangat bergantung pada negaranya.
Bidang keamanan pangan berikut relevan dengan pernyataan ini:
- Pestisida dan residu pestisida
- Obat hewan dan antibiotik
- Hormon pemacu pertumbuhan
- Cemaran (logam berat, PFAS, PCB, dioksin, nitrat)
- Patogen (Salmonella, Campylobacter, dll.)
- Peternakan dan pakan
- Pengawasan, impor, penarikan produk, pelabelan
Telur · Unggas · Produk susu · Ikan dan hasil laut · Daging merah · Buah dan sayuran
Pilih negara untuk melihat informasi yang telah diperiksa untuk negara tersebut.
Batasan: aturan hukum menggambarkan apa yang diizinkan, bukan apa yang terkandung dalam setiap makanan. Data pengukuran berasal dari sampel dan hanya bermakna bersama rincian metodenya.
Negara tempat tinggal atau pembelian Bandingkan dengan negara lain
Referensi
- Multidrug-Resistant Staphylococcus aureus in US Meat and Poultry.. Waters AE et al.. Clin Infect Dis 2011 · PMID 21498385 · DOI 10.1093/cid/cir181
- Dutch patients, retail chicken meat and poultry share the same ESBL genes, plasmids and strains.. Leverstein-van Hall MA et al.. Clin Microbiol Infect 2011 · PMID 21463397 · DOI 10.1111/j.1469-0691.2011.03497.x
- Extended-spectrum β-lactamase genes of Escherichia coli in chicken meat and humans, The Netherlands.. Overdevest I et al.. Emerg Infect Dis 2011 · PMID 21762575 · DOI 10.3201/eid1707.110209
- Global trends in antimicrobial use in food animals.. Van Boeckel TP et al.. Proc Natl Acad Sci U S A 2015 · PMID 25792457 · DOI 10.1073/pnas.1503141112
- Fluoroquinolone-resistant Campylobacter infections: eating poultry outside of the home and foreign travel are risk factors.. Kassenborg HD et al.. Clin Infect Dis 2004 · PMID 15095200 · DOI 10.1086/381597
- Fluoroquinolone-resistant Campylobacter species and the withdrawal of fluoroquinolones from use in poultry: a public health success story.. Nelson JM et al.. Clin Infect Dis 2007 · PMID 17342653 · DOI 10.1086/512369
- Emergence of plasmid-mediated colistin resistance mechanism MCR-1 in animals and human beings in China: a microbiological and molecular biological study.. Liu YY et al.. Lancet Infect Dis 2016 · PMID 26603172 · DOI 10.1016/S1473-3099(15)00424-7
- Lower prevalence of antibiotic-resistant Enterococci on U.S. conventional poultry farms that transitioned to organic practices.. Sapkota AR et al.. Environ Health Perspect 2011 · PMID 21827979 · DOI 10.1289/ehp.1003350
- National Outbreak of Multidrug Resistant Salmonella Heidelberg Infections Linked to a Single Poultry Company.. Gieraltowski L et al.. PLoS One 2016 · PMID 27631492 · DOI 10.1371/journal.pone.0162369
- Broiler chickens, broiler chicken meat, pigs and pork as sources of ExPEC related virulence genes and resistance in Escherichia coli isolates from community-dwelling humans and UTI patients.. Jakobsen L et al.. Int J Food Microbiol 2010 · PMID 20656368 · DOI 10.1016/j.ijfoodmicro.2010.06.025
- Restricting the use of antibiotics in food-producing animals and its associations with antibiotic resistance in food-producing animals and human beings: a systematic review and meta-analysis.. Tang KL et al.. Lancet Planet Health 2017 · PMID 29387833 · DOI 10.1016/S2542-5196(17)30141-9
- The European Union summary report on antimicrobial resistance in zoonotic and indicator bacteria from humans, animals and food in 2021-2022.. EFSA, ECDC. EFSA J 2024 · PMID 38419967 · DOI 10.2903/j.efsa.2024.8583
- Antimicrobial resistance profiles and virulence genotyping of Salmonella enterica serovars recovered from broiler chickens and chicken carcasses in Egypt.. Elkenany R et al.. BMC Vet Res 2019 · PMID 31029108 · DOI 10.1186/s12917-019-1867-z
- Overview of Colistin Resistance in the Middle East and North Africa (MENA) Region.. Saniour R et al.. Microorganisms 2026 · PMID 42655038 · DOI 10.3390/microorganisms14081693
- The European Union Summary Report on Antimicrobial Resistance in zoonotic and indicator bacteria from humans, animals and food in 2023-2024. EFSA and ECDC. EFSA J 2026 · DOI 10.2903/j.efsa.2026.9887
- Antimicrobial use in animal farms in Egypt: rates, patterns, and determinants.. ElSayed N et al.. J Egypt Public Health Assoc 2025 · PMID 39828782 · DOI 10.1186/s42506-024-00180-w
- World Health Organization (WHO) guidelines on use of medically important antimicrobials in food-producing animals.. Aidara-Kane A et al.. Antimicrob Resist Infect Control 2018 · PMID 29375825 · DOI 10.1186/s13756-017-0294-9
- Assessment of antibiotic residues in chicken meat.. Kamouh HM et al.. Open Vet J 2024 · PMID 38633178 · DOI 10.5455/OVJ.2024.v14.i1.40
- MRSA in conventional and alternative retail pork products.. O'Brien AM et al.. PLoS One 2012 · PMID 22276147 · DOI 10.1371/journal.pone.0030092
- Regulation (EC) No 1831/2003 on additives for use in animal nutrition (original text, Article 11 and recitals 25-26). European Parliament and Council. Official Journal of the EU (copy at legislation.gov.uk) 2003
- Health risk assessment of enrofloxacin, oxytetracycline, and sulfadimidine residues in broiler chicken carcasses marketed in Mit Ghamr, Egypt.. Noah SM et al.. Sci Rep 2026 · PMID 42527435 · DOI 10.1038/s41598-026-63227-2
- Attributable sources of community-acquired carriage of Escherichia coli containing beta-lactam antibiotic resistance genes: a population-based modelling study.. Mughini-Gras L et al.. Lancet Planet Health 2019 · PMID 31439317 · DOI 10.1016/S2542-5196(19)30130-5